Results 111 to 120 of about 345,966 (306)

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

Advanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park, Zahra Rezaei, Nam Ho Bae, Donggee Rho, Da‐Seul Kim, EunYoung Go, YoungTae Seo, Seok Jae Lee, Won Chan Seo, Luke P. Lee, HeaYeon Lee, Su Ryon Shin   +11 more
wiley   +1 more source

Population health profile of the NSW Outback Division of General Practice: supplement [PDF]

, 2007
© Commonwealth of Australia To view the data presented in the profiles in Excel spreadsheets or via Interactive Mapping, please see the PHIDU website at: www.publichealth.gov ...
Ambrose, S., Glover, J., Hutchison, A., Leahy, K.   +3 more
core   +1 more source

Astrocytic Phenotypic Switching in Posterior Piriform Cortex Orchestrates Bone Cancer Pain–Depression Comorbidity via Purinergic–Noradrenergic Signaling

Advanced Science, EarlyView.
Bone cancer pain and depression share a common origin: astrocytic A2‐to‐A1 transition in the posterior piriform cortex. This phenotypic shift disrupts the ATP–adenosine–A2AR–norepinephrine axis, simultaneously driving nociceptive and affective dysfunction.
Jiang‐Ping Liu, Jun‐Han Zhang, Zhi‐Xuan Tan, Wei‐Bing Yan, Ya‐Ru Yuan, Yao Liu, Bing‐Di Wei, Meng‐Qi Ding, Zhuo‐Min Fu, Ying Liu, An‐Qi Wang, Lin Ma, Yong‐Hong Li, Er‐Qing Chai, Chao‐Jun Wei   +14 more
wiley   +1 more source

Systemic Immune Inflammatory Index of Patients With Idiopathic Sudden Sensorineural Hearing Loss: Comparison of NLR and PRL Values

Ear, Nose & Throat Journal, 2021
Şahin Ulu MD, Abdullah Kınar MD, Abdulkadir Bucak MD, Murat Özdemir MD   +3 more
doaj   +1 more source

An audit of Ear, Nose and Throat diseases in a tertiary health institution in South-western Nigeria

The Pan African Medical Journal, 2013
INTRODUCTION: This study is aimed at determining the pattern of ear, nose and throat diseases and their relationship with socio-demographic factors with auditing intent in a tertiary hospital in South-western Nigeria. METHODS: Medical records of patients
Ayotunde James Fasunla, Musa Samdi, Onyekwere George Nwaorgu   +2 more
doaj   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance. [PDF]

, 2019
IntroductionMucopolysaccharidosis (MPS) VI or Maroteaux-Lamy syndrome (253200) is an autosomal recessive lysosomal storage disorder caused by deficiency in N-acetylgalactosamine-4-sulfatase (arylsulfatase B).
Akyol, Mehmet Umut, Alden, Tord D, Amartino, Hernan, Ashworth, Jane, Belani, Kumar, Berger, Kenneth I, Borgo, Andrea, Braunlin, Elizabeth, Eto, Yoshikatsu, Giugliani, Roberto, Gold, Jeffrey I, Harmatz, Paul, Hendriksz, Christian, Jester, Andrea, Jones, Simon A, Karsli, Cengiz, Mackenzie, William, Marinho, Diane Ruschel, McFadyen, Andrew, McGill, Jim, Mitchell, John J, MPS Consensus Programme Co-Chairs, MPS Consensus Programme Steering Committee, Muenzer, Joseph, Okuyama, Torayuki, Orchard, Paul J, Scarpa, Maurizio, Stevens, Bob, Thomas, Sophie, Walker, Robert, Wynn, Robert   +30 more
core  

Toxicity of lunar dust

, 2012
The formation, composition and physical properties of lunar dust are incompletely characterised with regard to human health. While the physical and chemical determinants of dust toxicity for materials such as asbestos, quartz, volcanic ashes and urban ...
Alving, Asano, Basu, Bice Fubini, Bosquillon, Brain, Brown, Brunetto, Butler, Cain, Cain, Castranova, Castranova, Christoffersen, Dag Linnarsson, Damm, Darquenne, Darquenne, Darquenne, Darquenne, Darquenne, David J. Loftus, Dockery, Driscoll, Erin M. Tranfield, Ewing, Fanizza, Fenoglio, Fenoglio, Fenoglio, Fenoglio, Frampton, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fubini, Fujishima, G. Kim Prisk, Gaier, Geiser, Gerde, Gerde, Ghiazza, Gustafsson, Hardy, Hardy, Harmsen, Heinrich, Hemmingsson, Heyder, Hill, Hong, Horanyi, Horwell, Horwell, Hurowitz, Ialenti, Ignarro, James, James, James Carpenter, Jones, Kamp, Kane, Karlsson, Khan-Mayberry, Kharitonov, Kharitonov, Kobrick, Lam, Lane, Lars L. Karlsson, Larsen, Latch, Lison, Lison, Liu, Liu, Loftus, Lucey, Lundberg, Lynch, MacLoughlin, McClellan, McKay, McKay, Moller, Mossman, Nel, Nel, Nemmar, Nikula, Norde, Oberdörster, Oberdörster, Oberdörster, Oberdörster, Park, Parsegian, Patil, Pauluhn, Pauluhn, Pawloski, Per Gerde, Persson, Peters, Peters, Peters, Peterson, Pezerat, Pope, Pope, Popov, Porter, Rask, Ricciardolo, Saffiotti, Sahai, Sakagami, Sakagami, Samet, Sanchez, Santana, Scheuch, Schwartz, Seagrave, Seaton, Seaton, Selg, Semmler, Shukla, Smaldone, Stahlhofen, Stanton, Sundblad, Taylor, Taylor, Taylor, Taylor, Thompson, Tranfield, Tronde, Tsuda, Turci, Turci, Urs Staufer, Vallyathan, van Eeden, von Klot, Wallace, Warheit, Warheit, West, Wim van Westrenen, Wong, Zanobetti   +159 more
core   +1 more source

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source