Results 121 to 130 of about 28,273 (262)

CRISPR Screens Identify PIK3C2A as a Novel Mediator of EGFR Inhibitor Resistance in Head and Neck Squamous Cell Carcinoma

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is a malignancy with poor prognosis and survival. While epidermal growth factor receptor (EGFR) is a known driver of HNSCC, EGFR inhibitors show limited efficacy as monotherapies, suggesting that effective combination therapies are needed.
Jiayu Wang   +13 more
wiley   +1 more source

Merkel Cell Carcinoma: Evolving Therapeutics, Continued Challenges

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine malignancy with rising incidence, influenced by ultraviolet (UV) radiation and Merkel cell polyomavirus (MCPyV). Methods This review summarizes recent advances in MCC management, based on an analysis of current literature, focusing on immune checkpoint inhibitors (ICIs)
Hunter A. Holley   +6 more
wiley   +1 more source

Diagnostic Accuracy of HPV Circulating Tumor DNA Following Non‐Diagnostic FNA of a Cystic Lateral Neck Mass

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Cystic lateral neck masses in adults commonly represent nodal metastases from HPV‐associated oropharyngeal squamous cell carcinoma (OPSCC) or benign lesions. Because cystic lesions are relatively acellular, fine‐needle aspiration (FNA) is often non‐diagnostic.
Michael R. Papazian   +4 more
wiley   +1 more source

Exploring Transitions in Care Among Patients With Head and Neck Cancer: A Scoping Review

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Individuals living with and beyond head and neck cancer (HNC) experience many transitions in care (TiC), as their treatment and care involve a team of multidisciplinary healthcare providers across a variety of settings. TiC can be associated with medical error, patient dissatisfaction with care, and overuse of healthcare resources ...
L. Fillo   +9 more
wiley   +1 more source

Effect of a Home‐Based Exercise Program on Muscle Mass, Fatigue, and Health‐Related Quality of Life Among Patients with Oral Cancer: A Randomized Trial

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Patients with head and neck cancer (HNC) often experience deteriorated health‐related quality of life (HRQoL) and loss of body weight and muscle mass. The primary aim was to determine if a home‐based exercise program, aiming to increase physical activity (PA), could reduce muscle mass loss and fatigue.
Camilla Wallmander   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy