Identification and localization of Nup170 in the microsporidian Nosema bombycis
Parasitology Research, 2021As one of the core framework proteins of nuclear pore complex (NPC), nucleoporin Nupl70 acts as a structural adapter between the nucleolus and nuclear pore membrane and maintains the stability of NPC structure through interaction with other proteins. In this study, we identified a Nup170 protein in the microsporidian Nosema bombycis for the first time ...
Ruisha Shang +9 more
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Advances in the Genetic Manipulation of Nosema bombycis
2022The microsporidium Nosema bombycis can infect and transmit both vertically and horizontally in multiple lepidopteran insects including silkworms and crop pests. While there have been several studies on the N. bombycis spore, there have been only limited studies on the N. bombycis sporoplasm.
Tian, Li, Junhong, Wei, Guoqing, Pan
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Hemocytin facilitates host immune responses against Nosema bombycis
Developmental & Comparative Immunology, 2020Invertebrates lack an adaptive immune response and thus are reliant on their innate immune response for eliminating invading pathogens. The innate immune responses of silkworms against the pathogen Nosema bombycis include: hemocyte aggregation, melanization, antimicrobial peptides, etc.
Wenjia, Ni +7 more
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STING-dependent autophagy suppresses Nosema bombycis infection in silkworms, Bombyx mori
Developmental & Comparative Immunology, 2021Nosema bombycis is a unicellular spore-forming obligate parasite, related to fungi, and causes infections in economically important animals and are opportunistic human pathogens. However, the mechanisms of host response to N. bombycis remain unclear. STING (stimulator of interferon genes) is an adapter protein involved in the innate immune response to ...
Xiaoting, Hua +3 more
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Identification and subcellular localization of NbIAP in the microsporidian Nosema bombycis
Journal of Invertebrate Pathology, 2022Many organisms go through a process of programmed cell death called apoptosis while newer cells are created. This has the effect of protecting the organism from cellular parasites and is a major line of defense against invading organisms. Apoptosis inhibitors, then, play an important role in aiding infectious agents by inhibiting caspase protease and ...
Feng Zhu +6 more
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DNA Probes for Two Microsporidia, Nosema bombycis and Nosema costelytrae
Journal of Invertebrate Pathology, 1995Two DNA fragments which hybridize specifically with DNA of Nosema bombycis and Nosema costelytrae, respectively, were obtained from genomic DNA of each microsporidian species and sequenced. Neither fragment hybridized with genomic DNA from four other microsporidian isolates tested: Nosema apis, Vairimorpha sp. from cabbage white butterfly (Pieris rapae)
L A, Malone, C A, McIvor
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A specific molecular label for identifying mature Nosema bombycis spores
Journal of Invertebrate Pathology, 2020Microsporidia are a fascinating phylum of obligate intracellular pathogens with unique infection processes and complicated life cycles. Microsporidian life cycles can be divided roughly into intracellular and extracellular stages. Currently, research on their life cycles were mainly explored by morphology because there are few molecular markers ...
Shiyi, Zheng +6 more
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Septin homologs cooperating in the Proliferative Stage of Microsporidia Nosema bombycis
Journal of Invertebrate Pathology, 2021The single-celled pathogen Nosema bombycis, that can infect silkworm Bombyx mori and other lepidoptera including Spodoptera, is the first identified Microsporidia which has diplokaryotic nuclei throughout the life cycle. Septin proteins can form highly ordered filaments, bundles or ring structures related to the cytokinesis in fungi. Here, three septin
Jun, Huang +9 more
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Inactivation and mechanisms of chlorine dioxide on Nosema bombycis
Journal of Invertebrate Pathology, 2010Biological tests demonstrated that the inactivation of Nosema bombycis (N. bombycis) spores by chlorine dioxide (ClO(2)) occurs very fast and is highly sensitive. The lowest effective inactivation dosage and time was 15mg/mL for 30min. The inactivation of spores was additionally verified by using double color fluorescence stain and spore germination ...
Zhengyong, Wang +6 more
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Natural selection maintains the transcribed LTR retrotransposons in Nosema bombycis
Journal of Genetics and Genomics, 2010Eight intact LTR retrotransposons (Nbr1-Nbr8) have been previously characterized from the genome of Nosema bombycis, a eukaryotic parasite with a compact and reduced genome. Here we describe six novel transcribed Nbr elements (Nbr9-Nbr14) identified through either cDNA library or RT-PCR.
Heng, Xiang +7 more
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