Results 101 to 110 of about 3,415,496 (317)

Parkinson's‐Linked LRRK2 and GBA1 Mutations Modulate the Peripheral Immune Response to Pseudomonas aeruginosa

Movement Disorders, EarlyView.
Abstract Background Peripheral disease mechanisms such as immune dysregulation may contribute to Parkinson's disease (PD). To investigate interactions between common PD mutations and immune responses to environmental pathogens, we studied responses to Pseudomonas aeruginosa (P.
Julian R. Mark, Hannah A. Staley, Ann M. Titus, Julian Agin‐Liebes, Alicia Garrido, Laura Hughes, Nicolas Dzamko, Rebecca L. Wallings, Malú Gámez Tansey   +8 more
wiley   +1 more source

A Hospital Infection Management Department-Led Intervention to Improve the Pathogen Submission Rate Before Antimicrobial Therapy Using a FOCUS-PDCA Model

Infection and Drug Resistance
Lizhen Xu, Qiufang Tang, Yuxiang Guo, Dan Liu Department of Hospital Infection Management, Affiliated Jinhua Hospital, Zhejiang University School of Medicine, Jinhua, Zhejiang, People’s Republic of ChinaCorrespondence: Lizhen Xu, Department of Hospital ...
Xu L, Tang Q, Guo Y, Liu D
doaj  

Conjugate and 23-valent pneumococcal polysaccharide booster vaccination in asplenic patients with thalassemia major: A randomized clinical trial study

Caspian Journal of Internal Medicine, 2017
Background: Pneumococcal vaccine provides protection against invasive pneumococcal disease in population at risk. This study was conducted to compare the antibody response to 13-valent pneumococcal conjugate vaccine and 23-valent pneumococcal ...
Mohammad Sadegh Rezai, Javad Ghaffari, Mohammadreza Mahdavi, Amir Bahari, Shahram Ala   +4 more
doaj  

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

Surgical site infection after caesarean section. Space for post-discharge surveillance improvements and reliable comparisons [PDF]

, 2016
Surgical site infections (SSI) after caesarean section (CS) represent a substantial health system concern. Surveying SSI has been associated with a reduction in SSI incidence.
Agresta, A., Allocca, A., Ascenzi, M. P., Ascenzi, M. P., Baccaro, G., Barboni, P., Beggiato, S., Belvisi, V., Bianchi, U., Bianchini, C., Cammarota, M., Carbone, A., Caterini, A., Cava, M. C., Celiberti, A., Ciavarella, M., Ciccotosto, N., Cicogna, V. A., Cimaglia, Claudia, Clerici Bagozzi, F., Colantuono, G., Colazingari, G., Conti, E., Curzi, M., Dalla Vecchia, D., Del Borgo, C., Ferraro, Federica, Fiore, R., Fioriello, C., Forino, F., Grilli, E., Ippolito, Giuseppe, La Mura, A., Lanini, S., Lucarelli, B., Manzi, P., Marrone, R., MARZUILLO, CAROLINA, Masala, P., MASTROIANNI, Claudio Maria, Mondillo, V., Montesano, P., Morgante, A. S., Moscardini, M. L., Moscatelli, M. M., Natalini Raponi, G., Orazi, D., Pallozzi, L., Panepuccia, L., Parrocchia, S., Pignataro, R., Piscioneri, C., Piselli, Pierluca, Pitorri, A., Pittalis, Silvia, Pizziconi, G., Primavera, A., Puro, Vincenzo, Quintavalle, G., Raponi, R., Rendo, V., Riccioni, C., Ruscitti, Luca E., Saccoccio, O., Salera, E., Salvati, O., Saviano, R., Serafini, G., Sguazzini, G., Silvestri, A., Soscia, F., Spaziani, C., Squarcione, S., Tana, M., Ullucci, M., Vagni, V., Verginelli, F., VILLARI, Paolo, VULLO, Vincenzo, Zaino, P., Zarelli, L.   +80 more
core  

Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens

Small Structures, EarlyView.
Applications of DNA origami nanostructures in pathogen detection and antimicrobial drug delivery require their efficient and robust binding to bacterial cells. Here, the cell wall‐binding glycopeptide antibiotic vancomycin is conjugated to selected staple strands and displayed in multivalent arrangements on the DNA origami surface to facilitate the ...
Özge Coşkuner Leineweber, Bhanu K. Pothineni, Nils Schumann, Ulrike Hofmann, Christin Möser, David M. Smith, Guido Grundmeier, Yixin Zhang, Adrian Keller   +8 more
wiley   +1 more source

Mortality Benefit of Tranexamic Acid for Hemorrhage With Concurrent Traumatic Brain Injury: Outcomes From a Prospective Cohort Study in a High‐Trauma, Prolonged Care Setting

World Journal of Surgery, EarlyView.
Early TXA administration (≤ 3 h) in concurrent hemorrhage and TBI was significantly associated with a 22% reduction in mortality at 7 days. TXA treatment was also associated with a significant 29% lower odds of organ failure and non‐significant 11% odds of good neurologic recovery.
Julia M. Dixon, Adane F. Wogu, Maria D. Rodriguez, Dale Barnhart, Rachel Patel, Hendrick J. Lategan, George Oosthuizen, Janette Verster, Shaheem de Vries, Craig Wylie, EpiC Study Site Collaborators, Elaine Erasmus, Steven G. Schauer, Nee‐Kofi Mould‐Millman   +13 more
wiley   +1 more source

Nursing Care Model Based on Knowledge Management in Preventing Nosocomial Infection After Caesarean Section in Hospital [PDF]

, 2014
Introduction: Nosocomial infection is one indicator of the quality of health services in the community, which also determines the image of health care institutions becauseit was a major cause of morbidityand death rate (mortality) in hospital.
Ahsan, A. (Ahsan)
core  

Risk Factors for Bloodstream Infections in Critically Ill Children: Gram‐Negative Predominance and Complex Chronic Conditions

Acta Paediatrica, EarlyView.
ABSTRACT Aim Bloodstream infections (BSIs) remain a significant cause of mortality in paediatric intensive care units (PICUs). This study aimed to identify risk factors associated with the aetiology and outcomes of hospital‐acquired BSIs. Methods This retrospective study analysed 422 blood cultures with pathogenic growth collected from patients ...
Vanessa Vicenzi, Ian Teixeira e Sousa, Jefferson Pedro Piva   +2 more
wiley   +1 more source

Antimicrobial prescribing guidelines for horses in Australia

Australian Veterinary Journal, EarlyView.
The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses.
L Hardefeldt, K Thomas, S Page, J Norris, G Browning, C El Hage, A Stewart, J Gilkerson, G Muscatello, D Verwilghen, G van Galen, J Bauquier, R Cuming, B Reynolds, C Whittaker, E Wilkes, J Clulow, C Burden, L Begg   +18 more
wiley   +1 more source