Results 121 to 130 of about 179,257 (328)

Bacterial fitness shapes the population dynamics of antibiotic-resistant and -susceptible bacteria in a model of combined antibiotic and anti-virulence treatment [PDF]

open access: yesarXiv, 2014
Bacterial resistance to antibiotic treatment is a huge concern: introduction of any new antibiotic is shortly followed by the emergence of resistant bacterial isolates in the clinic. This issue is compounded by a severe lack of new antibiotics reaching the market.
arxiv  

Polymeric Anti‐Antibiotic Microparticles to Prevent Antibiotic Resistance Evolution

open access: yesSmall, EarlyView.
This study introduces sevelamer (SEV) microparticles as a repurposed adjuvant therapy to combat antimicrobial resistance. SEV microparticles effectively capture vancomycin (VAN) and daptomycin (DAP), preventing these last‐resort antibiotics from driving resistance.
Roya Koshani   +8 more
wiley   +1 more source

Microblogging violent attacks on medical staff in China: a case study of the Longmen County People’s Hospital incident

open access: yesBMC Health Services Research, 2017
Background A violent attack on medical staff in Guangdong Province, in which a female doctor at Longmen County People’s Hospital (LCPH) was severely injured by a knife-wielding patient, has drawn significant public attention to the phenomenon of hospital
Jia Tian, Li Du
doaj   +1 more source

Assessing the Calibration of Subdistribution Hazard Models in Discrete Time [PDF]

open access: yesarXiv, 2020
The generalization performance of a risk prediction model can be evaluated by its calibration, which measures the agreement between predicted and observed outcomes on external validation data. Here, methods for assessing the calibration of discrete time-to-event models in the presence of competing risks are proposed.
arxiv  

Association of Single Nucleotide Polymorphisms in Toll-like Receptors with Acinetobacter baumanii Infectionin a Chinese Population

open access: yesIranian Journal of Public Health, 2016
Background: During recent years, infection of Acinetobacter baumanii showed a rapid growth in hospitals and community. Toll-like receptors (TLRs) are the most important pattern recognition receptors, which play a critical role during recognizing invading
Lei HE   +6 more
doaj  

Evaluating hospital infection control measures for antimicrobial-resistant pathogens using stochastic transmission models: application to Vancomycin-Resistant Enterococci in intensive care units [PDF]

open access: yesarXiv, 2016
Nosocomial pathogens such as Methicillin-Resistant {\em Staphylococcus aureus} (MRSA) and Vancomycin-resistant {\em Enterococci} (VRE) are the cause of significant morbidity and mortality among hospital patients. It is important to be able to assess the efficacy of control measures using data on patient outcomes.
arxiv  

Infants With a Congenital Diaphragmatic Hernia Had Favourable Pulmonary Hypertension Outcomes at 1 Year of Age

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Pulmonary hypertension is frequent in neonates with a congenital diaphragmatic hernia, but long‐term data have been scarce. Our aim was to examine its prevalence, evolution and management and identify factors associated with its persistence.
Alice Dirickx   +7 more
wiley   +1 more source

Management of nurse shortage and its impact on pathogen dissemination in the intensive care unit

open access: yesEpidemics, 2014
Introduction: Studies provide evidence that reduced nurse staffing resources are associated to an increase in health care-associated infections in intensive care units, but tools to assess the contribution of the mechanisms driving these relations are ...
Jordi Ferrer   +6 more
doaj   +1 more source

Use of Antibiotics and Severe Bacterial Infections Within the First 6 Months of Life—A Population‐Based Cohort Study From East Denmark

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim To investigate antibiotic exposure and the incidence of severe bacterial infections during the first 6 months of life in preterm infants born between 28 and 37 weeks of gestation. Methods Retrospective population‐based study of preterm infants in East Denmark, 2019–2021.
Anna Bjerager Arnesen   +10 more
wiley   +1 more source

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