Results 151 to 160 of about 173,695 (279)

Development and Validation of an HPLC–UV Method for the Quantification of Cefepime in Human Plasma for Routine Clinical Monitoring

SEPARATION SCIENCE PLUS, Volume 9, Issue 3, March 2026.
ABSTRACT Cefepime, a broad‐spectrum fourth‐generation cephalosporin, is widely used to treat nosocomial infections. Dependence upon renal elimination makes its pharmacokinetics highly susceptible to changes in renal function, which are common in critically ill patients.
Maged Kharouba, Asma Aboelezz, Adham Elshamy, Aaron M. Cook, Melissa L. Thompson Bastin, Sherif Hanafy Mahmoud   +5 more
wiley   +1 more source

Cryo‐EM structures of a MexB–MexY chimeric efflux pump reveal that large open clefts are intrinsic to the MexY porter domain

Acta Crystallographica Section F, Volume 82, Issue 3, Page 83-93, March 2026.
In this study, cryo‐EM structures of the chimeric RND transporter MexBYB, composed of MexB and MexY, are presented, revealing distinct symmetric‐like and asymmetric conformations under apo and drug‐supplemented conditions. These structures show that the unusually large open clefts observed in MexBYB, similar to those in MexY, represent a unique ...
Jiye Wang, Kenta Tsutsumi, Mika Hirose, Ryosuke Nakashima, Takayuki Kato, Kunihiko Nishino, Atsushi Nakagawa, Eiki Yamashita   +7 more
wiley   +1 more source

High‐Flow Oxygen Therapy vs. Continuous Positive Airway Pressure in Hospitalised Bronchiolitis: A Meta‐Analysis

Acta Paediatrica, Volume 115, Issue 3, Page 527-535, March 2026.
ABSTRACT Aim To compare high‐flow oxygen therapy (HFOT) with continuous positive airway pressure (CPAP) in children with bronchiolitis aged < 24 months, using treatment failure, length of stay (LOS) in the paediatric intensive care unit (PICU), and adverse events as outcomes.
Patrik Laiho, Sauli Palmu, Eero Lauhkonen, Matti Korppi, Paula Heikkilä   +4 more
wiley   +1 more source

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

HIV Medicine, Volume 27, Issue 3, Page 477-484, March 2026.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto, M. Tritzali, A. Bamford, A. C. Bailey, E. G. H. Lyall, N. E. Mackie, N. Tickner, C. Foster, on behalf of the PVC   +8 more
wiley   +1 more source

Clinical value of PDCA circulation nursing in reducing nosocomial infection. [PDF]

Front Med (Lausanne)
Wang X, Gu L, Chen W, Ma C, Li R.
europepmc   +1 more source

Shifting Antimicrobial Susceptibility Patterns of Uropathogens: A 20‐Year Analysis of Urine Cultures

International Journal of Urology, Volume 33, Issue 3, March 2026.
ABSTRACT Objectives Antimicrobial resistance among uropathogens, particularly extended‐spectrum β‐lactamase (ESBL) production and fluoroquinolone (FQ) resistance, presents a significant challenge to treating urinary tract infections (UTIs). This study aimed to analyze 20‐year trends in antimicrobial susceptibility among key urinary isolates at a single
Shinichi Takebe, Masami Endo, Nanaho Demizu, Mei Tokumoto, Ryota Morinaga, Taku Mitome, Akitoshi Takizawa   +6 more
wiley   +1 more source

Clinical Prediction of Secondary Bloodstream Infections in Patients with Cerebral Infarction: A Nomogram-Driven Risk Assessment Model Based on LASSO Regression

Infection and Drug Resistance
Lei Zhang,1,2 Xiaojun Li,2,3 Donghao Cai,2,4 Chuangchuang Mei,2,4 Lu Lu2,5 1Department of Quality Control, Guangdong Provincial Second Hospital of Traditional Chinese Medicine, Guangzhou, Guangdong, 510095, People’s Republic of China; 2Guangdong ...
Zhang L, Li X, Cai D, Mei C, Lu L
doaj  

Evaluation of potential sources of nosocomial infection in endodontic practice: a hygienic study. [PDF]

BDJ Open
Voroshilov S, Harutyunyan B, Goginyan V, Solomonov M.   +3 more
europepmc   +1 more source

How Does Biological Sex Impact Mucosal Bacterial Infection? Mucosal Defenses and Bacterial Detection

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Urinary tract infections possess substantial sex disparities in the incidence, immune response, and progression of infection. Some of these distinctions may be due to sexual dimorphism in mucosal barriers or sex differences in the initial immune response to infection.
Laura Ramirez Finn, Molly A. Ingersoll
wiley   +1 more source

Knowledge, Attitude, and the Practice in Nosocomial Infection Control Among Afghan Healthcare Workers in Herat Afghanistan: A Cross-Sectional Study. [PDF]

Health Sci Rep
Masudi M, Ejaz E, Wardak MF, Rahimi A, Shayan NA, Obnial JC, Lucero-Prisno DE.   +6 more
europepmc   +1 more source