Results 11 to 20 of about 179,257 (328)

Structure Elucidation, Total Synthesis, Antibacterial In Vivo Efficacy and Biosynthesis Proposal of Myxobacterial Corramycin**

Angewandte Chemie International Edition, Volume 61, Issue 51, December 19, 2022., 2022
Corramycin is a novel natural product produced by the myxobacterium Corallococcus coralloides. The structure, extraordinary total synthesis and biosynthesis of the antibiotic is described for the first time. Its promise as an in vivo septicemia model, the absence of cross‐resistance with commonly used antibiotic classes, and the lack of cytotoxicity ...
Cédric Couturier, Sebastian Groß, Alexander von Tesmar, Judith Hoffmann, Selina Deckarm, Anouchka Fievet, Nelly Dubarry, Thomas Taillier, Christoph Pöverlein, Heike Stump, Michael Kurz, Luigi Toti, Sabine Haag Richter, Dietmar Schummer, Philippe Sizun, Michael Hoffmann, Ram Prasad Awal, Nestor Zaburannyi, Kirsten Harmrolfs, Joachim Wink, Emilie Lessoud, Thierry Vermat, Veronique Cazals, Sandra Silve, Armin Bauer, Michael Mourez, Laurent Fraisse, Corinne Leroi‐Geissler, Astrid Rey, Stéphanie Versluys, Eric Bacqué, Rolf Müller, Stephane Renard   +32 more
wiley   +1 more source

Diagnostic and prognostic performance of urinary neutrophil gelatinase‐associated lipocalin in patients with cirrhosis and acute kidney injury

Hepatology, EarlyView., 2022
Diagnostic and prognostic ability of urinary NGAL in patients with cirrhosis and AKI. Abstract Background and Aims Acute kidney injury (AKI) commonly occurs in patients with decompensated cirrhosis. Urinary neutrophil gelatinase–associated lipocalin (uNGAL) could help discriminate between different etiologies of AKI.
Carmine Gambino, Salvatore Piano, Matteo Stenico, Marta Tonon, Alessandra Brocca, Valeria Calvino, Simone Incicco, Nicola Zeni, Roberta Gagliardi, Chiara Cosma, Martina Zaninotto, Patrizia Burra, Umberto Cillo, Daniela Basso, Paolo Angeli   +14 more
wiley   +1 more source

Charting the landscape of the environmental exposome

iMeta, Volume 1, Issue 4, December 2022., 2022
We describe the biological and chemical components of the environmental exposomes in three major environmental matrices that are highly relevant to human and social‐economical health—air, soil, and water. We discuss how different exposome components can interact with each other. Finally, we propose a list of outstanding challenges to be tackled to push
Xin Wei, Zinuo Huang, Liuyiqi Jiang, Yueer Li, Xinyue Zhang, Yuxin Leng, Chao Jiang   +6 more
wiley   +1 more source

In vitro cytocompatibility and antibacterial studies on biodegradable Zn alloys supplemented by a critical assessment of direct contact cytotoxicity assay

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 111, Issue 2, Page 241-260, February 2023., 2023
Abstract In vitro cytotoxicity assessment is indispensable in developing new biodegradable implant materials. Zn, which demonstrates an ideal corrosion rate between Mg‐ and Fe‐based alloys, has been reported to have excellent in vivo biocompatibility.
Maria Wątroba, Wiktor Bednarczyk, Piotr K. Szewczyk, Jakub Kawałko, Krzysztof Mech, Alina Grünewald, Irem Unalan, Nicola Taccardi, Gabriela Boelter, Manuel Banzhaf, Caroline Hain, Piotr Bała, Aldo R. Boccaccini   +12 more
wiley   +1 more source

Probability of Target Attainment Analyses to Inform Ceftolozane/Tazobactam Dosing Regimens for Patients With Hospital‐Acquired or Ventilator‐Associated Bacterial Pneumonia and End‐Stage Renal Disease Receiving Intermittent Hemodialysis

The Journal of Clinical Pharmacology, Volume 63, Issue 2, Page 166-171, February 2023., 2023
Abstract ASPECT‐NP, a phase 3 trial of ceftolozane/tazobactam in hospital‐acquired/ventilator‐associated bacterial pneumonia (HABP/VABP), excluded patients with end‐stage renal disease (ESRD). A modeling/simulation approach was undertaken to inform optimal dosing in this population, using previously developed ceftolozane and tazobactam population ...
Hwa‐Ping Feng, Yogesh T. Patel, Zufei Zhang, Jill Fiedler‐Kelly, Christopher J. Bruno, Elizabeth G. Rhee, Carisa De Anda, Wei Gao   +7 more
wiley   +1 more source

Investigation of the occupational exposure to blood-borne pathogens of staff at a third-class specialist hospital in 2015–2018: a retrospective study

Scientific Reports, 2022
To understand the current situation of occupational exposure to blood-borne pathogens in a women's and children's hospital and analyze the causes to provide a scientific basis for improving occupational exposure prevention and control measures.
Yuanyi Ji, Junbo Huang, Guoguo Jiang, Qiaolan Liu, Dalei Xiao, Jianjun Deng   +5 more
doaj   +1 more source

Occult Nosocomial Infections [PDF]

Infection Control & Hospital Epidemiology, 1998
AbstractEven with a good surveillance program, nosocomial infections may be not recognized because of several reasons: absence of symptoms or prolonged incubation period (eg, viral bloodborne infections, tuberculosis); problems with the microbiological diagnosis, because adequate specimens may be difficult to obtain or special methods should be used ...
Petignat, Christiane, Blanc, Dominique S., Francioli, Patrick   +2 more
openaire   +3 more sources

Risk Factors for Nosocomial Infection in the Neonatal Intensive Care Unit by the Japanese Nosocomial Infection Surveillance (JANIS) [PDF]

, 2008
We evaluated the infection risks in the neonatal intensive care unit (NICU) using data of NICU infection surveillance data. The subjects were 871 NICU babies, consisting of 465 boys and 406 girls, who were cared for between June 2002 and January 2003 in ...
Babazono, Akira, Doi, Hiroyuki, Hayakawa, Masahiro, Ibara, Satoshi, Kitajima, Hiroyuki, Nakamura, Tomohiko, Nakayama, Hideki, Nishimaki, Shigeru, Sato, Kazuo, Shiga, Seigo, Tanaka, Tahei, Une, Hiroshi   +11 more
core   +1 more source

Nosocomial infections surveillance [PDF]

Vojnosanitetski pregled, 2006
Epidemioloski nadzor podrazumeva sistematsko prikupljanje, analizu i tumacenje podataka o određenoj bolesti, kao i povratnu informaciju onima koji ucestvuju u prikupljanju podataka ili njihovom koriscenju, a radi sprecavanja i suzbijanja poremecaja zdravlja .
Ljiljana Markovic-Denic, Vesna Šuljagić   +1 more
openaire   +3 more sources

A Descriptive Study of Nosocomial Infections in an Adult Intensive Care Unit in Fiji: 2011-12 [PDF]

, 2016
Copyright © 2014 Keshni Naidu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited ...
Bissell, Karen, Graham, Stephen M, Nabose, Ilisapeci, Naidu, Keshni, Ram, S, Viney, Kerri   +5 more
core   +1 more source