Results 141 to 150 of about 7,585,604 (237)

Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Exploratory Analysis of Bone Marrow IL-10 and Plasma IL-1RA in Acute Traumatic Versus Chronic Non-Traumatic Orthopedic Patients: A Prospective Observational Study. [PDF]

Pathophysiology
Zaatar MT, Kattoura A, Aasar B, Othman R, Hallit S, Karam M, Fajloun Z, Roufayel R, Haroun R, Khalil R, Tannoury B, Kattoura F, Moussa MEH, Lahoud JC, Tawk C, Hoyek F.   +15 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Advancing annually resolved oxygen isotope dendrochronology to overcome wood-dating limitations in the Euro-Atlantic region. [PDF]

PLoS One
Rodríguez-Morata C, Davies D, Loader NJ, McCarroll D, Van Daalen S, Haneca K, Daux V, Domínguez-Delmás M.   +7 more
europepmc   +1 more source

Positions Available

Poultry Science, 2019
openaire   +2 more sources

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Increasing lifetime exposure to extreme fire weather under climate change in Europe. [PDF]

Environ Res Lett
Pietroiusti R, Hetzer J, Turco M, Laridon A, Lejeune Q, Prudencio Montaño S, Paprotny D, Thiery W.   +7 more
europepmc   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

An assessment of data and code sharing in research funded by the Nathan Shock Centers, 2017-2022: a meta-research study. [PDF]

Innov Aging
Vorland CJ, Chung S, Kramer AS, Hultquist JR, Allison DB, Brown AW.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source