Results 41 to 50 of about 3,868,289 (277)

Multilevel Methods for Uncertainty Quantification of Elliptic PDEs with Random Anisotropic Diffusion [PDF]

open access: yes, 2017
We consider elliptic diffusion problems with a random anisotropic diffusion coefficient, where, in a notable direction given by a random vector field, the diffusion strength differs from the diffusion strength perpendicular to this notable direction. The
Harbrecht, Helmut, Schmidlin, Marc
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Research and Medical Students: Some Notable Contributions Made in History

open access: yesJournal of Nepal Medical Association, 2020
The practice of medicine has started since the existence of humankind on the earth. But the commencement of scientific and evidence-based medicine cannot be traced back so far.
Pravakar Dawadi, Sabina Khadka
doaj   +1 more source

Menorah Review (No. 72, Winter/Spring, 2010) [PDF]

open access: yes, 2010
A Philosopher Rediscovers His Jewish Roots -- An Extraordinary Rabbinic Life -- An Interpretation of Isiah 6.8-10 -- Books in Brief: New and Notable -- Moreshet: From the Classics -- The Noah Affair -- Who Owns and Who is Responsible for a ...

core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Menorah Review (No. 81, Summer/Fall, 2014) [PDF]

open access: yes, 2014
Books in Brief: New and Notable -- candelabra gold -- Education: Yeshivah style -- Moreshet: From the Sources -- Mysteries of the Books of Job: From Elihu to Elie Wiesel -- Two Nations Are In Your Womb (Gen 25:23) -- When Rhetoric Dominates The Message --

core   +1 more source

Report on advances for pediatricians in 2018: allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroenterology, infectious diseases, neonatology, nutrition, respiratory tract disorders and surgery. [PDF]

open access: yes, 2019
This review reported notable advances in pediatrics that have been published in 2018. We have highlighted progresses in allergy, cardiology, critical care, endocrinology, hereditary metabolic diseases, gastroenterology, infectious diseases, neonatology ...
Bernasconi S   +10 more
core   +2 more sources

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Menemencioğulları İle İlgili Arşiv Belgeleri II

open access: yesBelgeler, 2009
Menemencioğulları Tarsus ve KaraisalI tarafında XVIII. yüzyılda ortaya çıkan ve XIX. yüzyılda bütün Çukurova’da etkili olan Türkmen kökenli bir a‘yân ailesidir.“Menemencioğulları İle İlgili Arşiv Belgeleri I” isimli makalemizde İstanbul’da Başbakanlık ...
Yılmaz Kurt
doaj  

A mini-review on Biginelli adducts with notable pharmacological properties

open access: yesJournal of Advanced Research, 2015
Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3,4-dihydropyrimidin-2(1H)-ones/thiones (DHPMs) have emerged as prototypes for the design of compounds with a broad variety of biological activities.
Ângelo de Fátima   +6 more
doaj   +1 more source

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