Results 41 to 50 of about 1,255,044 (248)
A notable Ichthyological find in the Kruger National Park
A notable ichthyological find has been made in the Kruger National Park with the recording, during April 1970, of a specimen of the marine fish, Acanthopagrus berda Forskal) near the confluence of the Crocodile and Komati Rivers. This is the first record
U de V. Pienaar
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Chej Maelainin, un notable sahariano
Chorfa, Haj, Alem y santo. Chej Maelainin, último de los grandes personajes del Sáhara nació en el seno de una familia de linaje chorfa, dedicada al estudio.
Ángela Hernández Moreno
doaj
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Un espectroscopio casero de notable performance
lt is possible to built an excellent low cost spectroscope using a piece of "compact disk" as a diffraction pattern, taking advantage of the excellent regularity and thinness of its lines. We presents in this paper the constructive details, some analysis
Lorenzo Marcos Iparraguirre
doaj
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
A mini-review on Biginelli adducts with notable pharmacological properties
Since the disclosure of Biginelli reaction by the chemist Pietro Biginelli, functionalized 3,4-dihydropyrimidin-2(1H)-ones/thiones (DHPMs) have emerged as prototypes for the design of compounds with a broad variety of biological activities.
Ângelo de Fátima +6 more
doaj +1 more source

