Results 141 to 150 of about 143,671 (257)

Notas de Población Vol.6 N° 16

open access: yes, 1978
Proyecciones demográficas preparadas por el CELADE / Jorge L. Somoza. -- Mortalidad en los primeros años de vida en la América Latina / Hugo Behm y Domingo Primante.

core  

Cryo‐EM Structure Guided Engineering of Botulinum Neurotoxin A With Advanced Receptor Binding Affinity and Therapeutical Benefits

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
The butterfly unfolded wing in an open form structure of botulinum neurotoxin type A (BoNT/A) at physiological‐state was confirmed at 2.85 Å resolution by cryo‐electron microscopy (cryo‐EM). Structure‐guided protein engineering significantly enhanced the receptor‐binding affinity, therapeutic efficacy, and safety of the engineered toxin variants ...
Wenrui Wang   +16 more
wiley   +1 more source

Notas de la CEPAL Nº 22

open access: yes, 2002
Número EspecialLa edición N° 22 de las Notas de la CEPAL está dedicadaíntegramente al documento Globalización y desarrollo,presentado por esta Comisión Regional de las Naciones Unidas en su Vigesimonovenoperíodo de sesiones.

core  

Endogenously generated Dutch‐type Aβ non‐fibrillar aggregates dysregulate presynaptic neurotransmission in the absence of detectable inflammation

open access: yesAlzheimer's &Dementia, Volume 22, Issue 6, June 2026.
Abstract BACKGROUND APPE693Q (“Dutch”) transgenic mice develop aging‐related learning deficits and accumulate endogenously generated non‐fibrillar aggregates (NFAs) of amyloid beta (Aβ) and amyloid precursor protein α‐carboxy terminal fragments. NFA‐Aβ correlates with synaptic loss and memory deficits more closely than does fibrillar Aβ.
Emilie L. Castranio   +28 more
wiley   +1 more source

Abnormalities of liver sinusoidal endothelial cells in primary biliary cholangitis. [PDF]

open access: yesWorld J Exp Med
Thalassinos E   +6 more
europepmc   +1 more source

Glacial refugia, postglacial dynamics, and hybrid zones of Pinaceae in Eurasia captured from sedimentary ancient DNA

open access: yesEcosphere, Volume 17, Issue 6, June 2026.
Abstract Boreal forests cover nearly one‐third of global forest area. Glacial cycles have shaped the distribution and connectivity of modern Pinaceae genera, yet species‐level refugia, postglacial migrations, and hybridization patterns remain unclear due to limited high‐resolution taxonomic and temporal data. We applied a hybridization capture approach
Stefano Meucci   +18 more
wiley   +1 more source

Organoids: From Bench to Bedside Applications

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li   +6 more
wiley   +1 more source

Forming a choir with total laryngectomized patients. [PDF]

open access: yesCodas
Monteiro JC, Paes SM, Azevedo RR.
europepmc   +1 more source

Notas biográficas

open access: yes, 2016
Notas biográficas, Notas biográficas
core   +1 more source

Scheffrahnitermes ubuntu (Isoptera: Apicotermitinae), Description of a New Termite Using a Collaborative Approach to Address the Wallacean Shortfall

open access: yesNew Zealand Journal of Zoology, Volume 53, Issue 2, June 2026.
The study of Neotropical Apicotermitinae remains challenging due to the large number of undescribed taxa (Linnean shortfall) as well as the scarcity of distributional data (Wallacean shortfall). Despite recent efforts to reduce the first one, the second remains an even more significant challenge.
Camila C. Mellado   +10 more
wiley   +1 more source

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