Results 141 to 150 of about 87,333,622 (247)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

"We don't get asked": including people with workforce experience as public contributors in a workforce-related study about homecare work towards the end-of-life. [PDF]

Res Involv Engagem
Roberts H, Begum S, Dale M, Elliott-Button H, Krygier J, Moss C, Johnson MJ, Walker L.   +7 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

[Note from J. P. Adamcik to L. C. Graves, December 2, 1963 #1]

, 1963
Note from J. P. Adamcik and K. L. Anderton to L. C.
Adamcik, J. P., Anderton, K. L.
core  

Editorial: Equity in cancer care: mechanisms and interventions for enhanced access. [PDF]

Front Oncol
Santos Salas A, Pujadas Botey A, Eala MA.   +2 more
europepmc   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Data from CREP Replication of Does Money Buy Happiness, Diener et al. (2010). [PDF]

J Open Psychol Data
Costa O, Feragen Q, Wagge J, Woodward AM.   +3 more
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Mexican International Railroad and its connections.

, 1895
Map shows the late nineteenth century Mexican railroad line. Includes legend, distance table, and two profiles of routes between Ciudad Porfirio Diaz and the Pacific Ocean; illustration of the International Bridge on title panel.
American Bank Note Company
core  

Your voice matters: using participatory film to engage people with chronic pain in public involvement and research. [PDF]

Res Involv Engagem
Harrisson SA, Begum S, Toussaint C, Agathangelou M, Rattee J, Holden MA, Canvin K.   +6 more
europepmc   +1 more source