Results 41 to 50 of about 5,996,016 (276)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Evidence of tutoring in the development of subsong in newly-fledged Meyer's Parrots Poicephalus meyeri

open access: yesAnais da Academia Brasileira de Ciências, 2004
Subsongs are vocal trials uttered by young birds to practice songs. Among songbirds, subsongs are displayed by individuals in their first year of life.
Simone Masin   +2 more
doaj   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Notes on Occupational Maladjustment and Managerial response in 36 large South African enterprizes

open access: yesSA Journal of Industrial Psychology, 1982
A survey was undertaken to assess the scope of certain mental health problems in work organizations and ways these are being dealt with by management. The general pattern emerging from the data reflects a growing awareness of and concern for problems of ...
A. Vlok
doaj   +1 more source

Lecture Notes on Network Information Theory [PDF]

open access: yes, 2010
These lecture notes have been converted to a book titled Network Information Theory published recently by Cambridge University Press. This book provides a significantly expanded exposition of the material in the lecture notes as well as problems and ...
Gamal, Abbas El, Kim, Young-Han
core   +1 more source

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

THE IMPACT OF EVENTS AFTER THE REPORTING DATE ON THE FINANCIAL POSITION AND PERFORMANCE OF BANKS [PDF]

open access: yesAkademičnij Oglâd
Banks maintain their accounting records and prepare financial statements in accordance with IFRS. Annual financial statements are a set of reports that characterize the financial position, results of the bank’s operations, cash flows and changes in ...
Oksana O. Kazak, Mariana O. Sulyma
doaj   +1 more source

Style and Uzus Labels of Adjectives in the Russian Language Dictionaries: a Comparative Quantitative and Qualitative Study

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics
The aim of the study is to examine the stylistic coloring of adjectives in Russian language dictionaries to establish similarities and differences in the use of vocabulary. The research material was eight dictionaries of the Russian language. The complex
Sharapat K. Mamirova   +2 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman   +8 more
wiley   +1 more source

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