Results 151 to 160 of about 38,174 (285)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Bioinspired and Architectured Materials with Enhanced Mechanical Performance by Three-dimensional Printing

, 2018
The tremendously rapid development of additive manufacturing technologies is enabling the fabrication of a new class of advanced materials, referred to as architectured materials.
Zorzetto, Laura
core  

Assessing the impact of safety guardrails on large language models using irritability metrics. [PDF]

NPJ Digit Med
Teferra BG, Johny N, Huang S, Rueda A, Kamaleddin MA, Dunlop K, Zhang Y, Jha M, Sharma D, Bhat V.   +9 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Canadian French translation of the BREAST-Q Breast Conserving Therapy module. [PDF]

J Patient Rep Outcomes
Rafinejad-Farahani B, Bernardini LC, Bourque JM, Koch CA, Rodin D.   +4 more
europepmc   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Editorial commitment to trust and integrity in science: implications for pain and anesthesiology research. [PDF]

Can J Anaesth
Palermo TM, Bouhassira D, Davis KD, Hemmings HC, Hurley RW, Katz J, Pandit JJ, Price TJ, Schatman ME, Schwarz SKW, Turk DC, Van de Velde M, Wiles MD, Yaksh TL, Yarnitsky D.   +14 more
europepmc   +1 more source

Biofiltres i nous materials per eliminar les olors de les emissions gasoses

, 2010
Els biofiltres són una alternativa eficient i sostenible per reduir les olors de les emissions gasoses. El contaminant és degradat per uns microorganismes que romanen adherits a un material de rebliment. El present treball avalua el rendiment de quatre biofiltres diferents, incloent novedosos materials híbrids, durant el tractament d'una mostra ...
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

How are we preparing doctors for their roles as patient educators? Exploring undergraduate and postgraduate curricula in Canadian medical schools. [PDF]

Can Med Educ J
Cohen A, Gomez-Garibello C, Steinert Y.
europepmc   +1 more source