Results 61 to 70 of about 866,056 (302)

Engineering Immunoregenerative Therapy via an Immunomodulatory Binary Pharmacology Hydrogel Depot for Prolonged Allograft Survival

open access: yesAdvanced Science, EarlyView.
An immunomodulatory hydrogel (iGEL) forms spontaneously upon subcutaneous injection, acting as a tissue‐adhesive depot. It releases anti‐rejection and regenerative agents in response to inflammation, suppressing T‐cell activity, promoting vascular repair, and restoring allograft function without systemic immunosuppression.
Ning Wang   +14 more
wiley   +1 more source

The Symbiotic Novae [PDF]

open access: yesInternational Astronomical Union Colloquium, 1988
AbstractSymbiotic Novae are composite spectrum variables, whose light history is characterized by a single nova-like outburst. Their behaviour and time evolution is rather similar to that of classical novae, except for the much longer time scale, and the associated physics could be the same.
openaire   +2 more sources

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

open access: yesAdvanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu   +7 more
wiley   +1 more source

Enhanced Antibacterial Properties of Lyotropic Liquid Crystalline Nanoparticles via Curvature Modulation

open access: yesAdvanced Science, EarlyView.
Lipid nanostructured particles with increasing negative Gaussian curvature progress from vesicles to P‐cubosomes and D‐cubosomes. This curvature hierarchy enhances interaction with bacterial membranes, promotes membrane remodeling and leakage, and potentiates daptomycin activity against MRSA.
Xiangfeng Lai   +10 more
wiley   +1 more source

Cidades Novas [PDF]

open access: yes, 2020
Uma viagem ao universo das cidades novas, esse é o convite que essa obra vem oferecer aos leitores a fim de transitar, a partir da visão particular do autor, pelo contexto, pelos conceitos e pelos aspectos inerentes a esse tipo urbanístico, ainda pouco explorado pela literatura especializada brasileira.
openaire   +2 more sources

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

open access: yesAdvanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu   +12 more
wiley   +1 more source

Recurrent novae [PDF]

open access: yesInternational Astronomical Union Colloquium, 1990
AbstractThermonuclear models of recurrent novae demand white dwarf accretors near the Chandrasekhar mass. In this case, the known recurrent novae should possess classical counterparts bearing the same structural parameters and space distribution, save for having only marginally less massive white dwarfs.
openaire   +1 more source

[CfA:] You can contribute to Heraldica Nova, too!

open access: yes, 2017
Paris, Sainte-Geneviève MS 1688, fol. 1 We are very happy to say that Heraldica Nova is becoming more and more popular amongst the international community of heraldists, historians, and enthusiasts engaging with heraldry in the medieval and early-modern ...
Heraldica Nova
core  

Experience‐Dependent Reorganization of Hippocampal CA3 Neuronal Ensembles Associates With Memory Generalization

open access: yesAdvanced Science, EarlyView.
Mice can transfer the learned rule of spatial working memory to guide similar but novel tasks. Hippocampal CA3 populational activity dynamically reorganize during memory generalization, shifting from task‐specific to generalized coding over testing days. Sparse yet redundant neural representations of CA3 enable rule transfer and cognitive map formation,
Da Song   +8 more
wiley   +1 more source

Chlorine‐Functionalized Silane‐Modified Copper Electrocatalyst for Enhanced CO2 Reduction to Multi‐Carbon Products

open access: yesAdvanced Science, EarlyView.
A chlorine‐functionalized silane modifier (CPTMS) is introduced to cooperatively regulate CO2 reduction to C2+ products on Cu‐based catalysts. Dual‐functional interface sequentially enhances CO2 activation, intermediates protonation and C─C coupling, delivering a 5‐fold increase in C2+ faradaic efficiency (FE, 75% vs.
Ying Ying Ch'ng   +14 more
wiley   +1 more source

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