Results 171 to 180 of about 460,117 (268)

Late-onset Hailey-Hailey disease with a novel frame-shift variant in the ATP2C1 gene

Journal of Cutaneous Immunology and Allergy
Hiroka Iwata, Hirohito Kotani, Ai Kuzumi, Natsuko Inagaki, Natsuko Inagaki, Shinichi Sato   +5 more
doaj   +1 more source

A novel variant in <i>SIAH1</i> associated with autosomal dominant Buratti-Harel syndrome. [PDF]

Front Neurosci
Zheng H, Zhang L, Li F.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

A new recombinant avian metapneumovirus vaccine candidate provides complete protection against the novel variant infectious bursal disease virus in chickens. [PDF]

Vet Res
Meng L, Chen Y, Yu M, Qi X, Liu Y, Wang S, Xue X, Zhang T, Fan W, Zhang Z, Wang Y, Guo R, Hu M, Zhang Y, Duan Y, Cui H, Gao Y.   +16 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Schimke immunoosseous dysplasia (SIOD): Delayed onset of rare disease and novel variant. [PDF]

Qatar Med J
Elshirbeny M, Nauman A, Abuhelaiqa E, Almalki H.   +3 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Comparative pathogenicity of very virulent and novel variant infectious bursal disease virus Egyptian strains in chickens. [PDF]

Virol J
Ibrahim M, Ayman D, Arafa W, Abdelmagid MA, El-Sanousi AA, Shaheen M.   +5 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Mucosal and skin pigmentation with abnormal nails

JEADV Clinical Practice
Fengming Chen, Ling Liu, Pingshen Fan
doaj   +1 more source