Results 211 to 220 of about 442,293 (268)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Functional analysis of a novel variant in the <i>COL5A1</i> gene in a Polish patient with the classical type of Ehlers-Danlos syndrome. [PDF]

Front Genet
Junkiert-Czarnecka A, Maciak K, Kacprzak MM, Łobodzińska A, Sobczyńska-Tomaszewska A, Jurkiewicz A, Gora M, Burzynska B, Pilarska-Deltow M, Haus O.   +9 more
europepmc   +1 more source

A novel variant leads to WT1-related nephrotic syndrome and differences of sex development: a case report. [PDF]

Front Pediatr
Gao S, Wang D, Ding X, Bai C, Nie N, Chang H, Zhang R, Liu J, Zhang Q, Liu L, Lin Y.   +10 more
europepmc   +1 more source

Corrigendum: A novel variant in <i>CLCN7</i> regulates the coupling of angiogenesis and osteogenesis. [PDF]

Front Cell Dev Biol
Peng H, He HB, Wen T.
europepmc   +1 more source

Infertility Due to a Novel Variant of a Balanced Y;1 Translocation: A Case Report. [PDF]

Cureus
Magnuson S, Doney K, Wesemann LB, Gross K.   +3 more
europepmc   +1 more source

A Novel Variant of ARID1B-Related Coffin-Siris Syndrome in a Saudi Girl: A Case Report. [PDF]

Cureus
Alquraishi AS, Rayees S, Saad MM, Alasmari H.   +3 more
europepmc   +1 more source

Novel variant in <i>PNPLA6</i> gene causes Oliver-McFarlane syndrome in a Chinese family: 13 years follow-up. [PDF]

Front Genet
Xiao P, Gu Y, Qi X, Li T, Zuo T, Xie Y, Zhang S, Sheng X.   +7 more
europepmc   +1 more source

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Variants of the Novel Coronavirus

Journal of Clinical Case Reports and Studies, 2022
The novel coronavirus had emerged in 2019 from the Hubei province in China. Now the world is facing the third and fourth waves of the pandemic caused by this virus. These are due to the new mutants and variants of the virus that have emerged over time due to various reasons. It is important to keep oneself updated about these mutants and variants.
Sayan Bhattacharyya, Amitabha Dan, Dipak Pal   +2 more
openaire   +1 more source

Response to: Naming a novel hemoglobin variant

Journal of Chromatography B, 2014
[No abstract available]
Wieland, Heinrich, Bisse, Emmanuel, Akar, Nejat   +2 more
openaire   +3 more sources

A Novel Variant of Glutamine

Diabetes, 2001
Glutamine:fructose-6-phosphate  amidotransferase(GFAT) is the rate-limiting enzyme of the hexosamine synthesis pathway. Products of this pathway have been implicated in insulin resistance and glucose toxicity. GFAT1 is ubiquitous, whereas GFAT2 is expressed mainly in the central nervous system.
John E. DeHaven, Katherine A. Robinson, Bryce A. Nelson, Maria G. Buse   +3 more
openaire   +1 more source