A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Alfredsson, L +8 more
core +2 more sources
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding +5 more
wiley +1 more source
Energy security and the “dual carbon” goals are impacting the global energy industry and supply chains, presenting some urgent needs for the secure, efficient, and green low-carbon transformation of energy and power systems in China.
Tong SI +5 more
doaj +1 more source
ERM Inhibition Confers Ferroptosis Resistance through ROS‐Induced NRF2 Signaling
ERM inhibition disrupts ERM‐actin interactions, elevating ROS and triggering KEAP1 degradation, which stabilizes and activates NRF2. Nuclear NRF2 induces cytoprotective genes, notably HMOX1, enhancing redox buffering and suppressing lipid peroxidation to resist erastin‐induced ferroptosis.
Menghao Qiao +19 more
wiley +1 more source
Research Progress on Passive NOx Adsorbers (PNAs) for Diesel Vehicles
The cold start phase of diesel engines represents a critical stage for nitrogen oxides (NOx) emissions, which pose significant challenges to environmental sustainability and public health.
Chuan GAO +5 more
doaj +1 more source
Thermodynamic model and optimization of a miller cycle applied on a turbocharged diesel engine
A new thermodynamic model for turbocharged diesel engines is developed for Miller cycle analysis and optimization. The effects of turbocharger efficiency, Miller degree, combustion mode, and air fuel ratio on engine efficiency, power, and NOx emissions ...
Yi CUI, Kangyao DENG
doaj +1 more source
Summertime distribution and relations of reactive odd nitrogen species and NOyin the troposphere over Canada [PDF]
We report here large-scale features of the distribution of NOx, HNO3, PAN, particle (NO3) (-) and NOy in the troposphere from 0.15 to 6 km altitude over central Canada.
Anderson, B +17 more
core +1 more source
Ultrasonic‐Assisted Photocatalytic Conversion of Air to Nitric Acid Under Ambient Conditions
Ultrasound‐assisted photocatalytic air oxidation to nitrate enhances soil nitrogen fertilizer dynamics, thereby enabling improved energy conversion efficiency and sustainable agriculture. ABSTRACT The production of nitric acid (HNO3) holds significant importance in the chemical industry, and achieving direct air‐to‐HNO3 conversion with high efficiency ...
Shiming Chen +11 more
wiley +1 more source
On-Board Sensor-Based NO x Emissions from Heavy-Duty Diesel Vehicles [PDF]
Real-world nitrogen oxides (NOx) emissions were estimated using on-board sensor readings from 72 heavy-duty diesel vehicles (HDDVs) equipped with a Selective Catalytic Reduction (SCR) system in California.
Boriboonsomsin, Kanok +9 more
core +2 more sources
Atomically Precise Clusterzymes: A Programmable Optoelectronic Platform for Neuroscience
Atomically precise clusterzymes, engineered via atomic and ligand design, serve as programmable platforms for neuroscience applications. They demonstrate tailored biocatalysis for neuroinflammation, tunable optical properties for deep‐tissue bioimaging and 3D visualization, and enhanced charge transfer for brain–computer interfaces.
Si Sun +6 more
wiley +1 more source

