Results 41 to 50 of about 120,595 (228)

Integrated Multiomic Analysis Reveals an EBV‐Associated MIF–SPP1+ Macrophage Axis Linking Tumor Stemness and Immune Dysfunction in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study maps how Epstein–Barr virus reshapes the cellular ecosystem of nasopharyngeal carcinoma. It identifies SPP1+ macrophages as partners of stemness‐associated tumor cells and dysfunctional T cells, links tumor‐derived MIF to macrophage recruitment and programming, and shows that macrophage‐derived SPP1 promotes tumorsphere formation and impairs
Guo‐Ying Liu, Shu‐Hui Lv, Shui‐Qing He, Yao‐Fei Jiang, Xing‐Si Peng, Jian‐Cong Sun, Fen He, Hai‐Yan Qin, Nian Lu, Wei‐Xin Bei, Lin‐Yu Zhao, Wan‐Qin Shen, Ze‐Yu Zhao, Lin Wang, Yan‐Qun Xiang, Wang‐Zhong Li   +15 more
wiley   +1 more source

Open-circuit fault diagnosis for a grid-connected NPC inverter with unity Power Factor

, 2015
This paper presents an open-circuit fault detection method for a grid-connected Neutral-Point Clamped (NPC) inverter. The open-circuit fault mainly occurs due to bonding wire failures like lift-off and crack in the power module where the thermal stress ...
Ui-Min Choi, Lee, Kyo-Beum, Blaabjerg, Frede; id_orcid, Frede Blaabjerg, Kyo-Beum Lee, Choi, Uimin, Lee, June-Seok, June-Seok Lee   +7 more
core   +1 more source

Harmonic Analysis of Single-Phase Neutral-Point-Clamped Cascaded Inverter in Advanced Traction Power Supply System Based on the Big Triangular Carrier Equivalence Method

Energies, 2018
An advanced traction power supply system based on a single phase neutral-point-clamped (NPC) cascaded inverter is studied. The big triangular carrier equivalence method in double coordinate system is proposed, which can reduce one coordinate system, thus
Pengcheng Han, Xiaoqiong He, Yi Wang, Haijun Ren, Xu Peng, Zeliang Shu   +5 more
doaj   +1 more source

Open-circuit fault diagnosis of NPC inverter IGBT based on independent component analysis and neural network

Energy Reports, 2020
Power switching devices are the core component of inverter, the fault diagnosis of power switching devices has very important significance for the reliability of inverter.
Hailin Hu, Fu Feng, Tao Wang
doaj   +1 more source

The Novel Viral Non‐Coding RNA LMP2A‐IT1 Promotes the Lytic Replication of EBV

Advanced Science, EarlyView.
Decades after its discovery, EBV's genome still harbours unannotated “dark matter”. LMP2A‐IT1, a novel EBV‐encoded transcript identified in this work, is strongly upregulated during lytic replication and promotes BZLF1 expression, likely through activation of inflammatory responses, thereby enhancing viral propagation in a self‐reinforcing positive ...
Zheng‐Zhou Lu, Jun‐Fei Wu, Nannan Zhu, Ming‐Hui Yang, Le‐Le Zhang, Yuan‐Tao Liu, Wei‐Jun Chen, Jin‐Kun Tang, Jia‐Wei Ge, Chao‐Bo Lei, Tao Zhang, Yu Wang, Chao‐Yun Huang, Qian Zhong, Mu‐Sheng Zeng, Yan Li   +15 more
wiley   +1 more source

Reinforced Droop for Active Current Sharing in Parallel NPC Inverter for Islanded AC Microgrid Application

Energies, 2019
The paper investigates the current sharing in parallel 3-level Neutral point clamped inverter for islanded AC microgrid application. In Distributed generation, parallel power electronic interface based microgrid suffers from power quality issues due to ...
Monica Purushotham, Kowsalya Muniswamy
doaj   +1 more source

Comparative Evaluation of Efficiency and Reliability of Single-Phase Five-Level NPC Inverters for Photovoltaic Systems

IEEE Access, 2021
It is required to reduce the cost of PV energy to be competitive as an alternative energy source. The efficiency and reliability of PV inverters are important aspects to be enhanced to reduce the cost of PV energy since they contribute to the reduction ...
Ui-Min Choi, Taerim Ryu
doaj   +1 more source

Targeting Mitochondrial Redox Signaling Promotes Neuroregeneration and Functional Recovery in a Multiple Sclerosis Model

Advanced Science, EarlyView.
Modulation of mitochondrial redox signaling by furapyrrodole activates CYB5R3 and suppresses Notch signaling, unlocking the regenerative potential of endogenous neural progenitor cells. This approach promotes neurogenesis, oligodendrogenesis, and remyelination, thereby improving neuronal function in a mouse model of multiple sclerosis and identifying ...
Yuki Narushima, Joshua Saylor, Shun Saito, Jinyan Zhou, Haruka Kawano, Shehata Anwar, Haruki Oba, Rachel Huezo, Miyu Okano, Haruki Matsuda, Makoto Kawatani, Kaori Honda, Hiroyuki Osada, Yuta Kikuchi, Masahito Ohue, Masami Ishibashi, Takayoshi Arai, Makoto Inoue, Midori A. Arai   +18 more
wiley   +1 more source

DTX3 Suppresses the NPM3–RUVBL1 Axis to Inhibit Homologous Recombination Repair and Abrogate Tumor Radioresistance

Advanced Science, EarlyView.
Deltex 3 (DTX3) catalyzes K27‐linked ubiquitination of nucleophosmin 3 to disrupt homologous recombination repair and reverse tumor radioresistance. Low DTX3 predicts poor survival and radiotherapy recurrence, serving as a radiosensitizing therapeutic target.
Jia‐Hao Xiao, Chang‐Jun Xie, Yan‐Hua Chen, Hao Cheng, Shuang‐Hui Li, Wei Li, Ya‐Wen Bin, Rui‐Min He, Ying‐Qing Li, Ping Feng   +9 more
wiley   +1 more source

Fault Diagnosis and Tolerant Control of Three-Level Neutral-Point Clamped Inverters in Motor Drives

Energies, 2020
This paper presents an extension theory-based assessment method to perform fault diagnosis for inverters in motor driving systems. First, a three-level neutral-point clamped (NPC) inverter is created using the PSIM software package to simulate faults for
Kuei-Hsiang Chao, Chen-Hou Ke
doaj   +1 more source