ATG6 interacting with NPR1 increases Arabidopsis thaliana resistance to Pst DC3000/avrRps4 by increasing its nuclear accumulation and stability [PDF]
eLifeAutophagy-related gene 6 (ATG6) plays a crucial role in plant immunity. Nonexpressor of pathogenesis-related genes 1 (NPR1) acts as a signaling hub of plant immunity. However, the relationship between ATG6 and NPR1 is unclear.
Baihong Zhang +9 more
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A Conserved Puccinia striiformis Protein Interacts with Wheat NPR1 and Reduces Induction of Pathogenesis-Related Genes in Response to Pathogens [PDF]
Molecular Plant-Microbe Interactions, 2016 In Arabidopsis, NPR1 is a key transcriptional coregulator of systemic acquired resistance. Upon pathogen challenge, NPR1 translocates from the cytoplasm to the nucleus, in which it interacts with TGA-bZIP transcription factors to activate the expression ...
Xiaodong Wang +5 more
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Role of NPR1 in Systemic Acquired Stomatal Immunity [PDF]
Plants, 2023 Stomatal immunity is the primary gate of the plant pathogen defense system. Non-expressor of Pathogenesis Related 1 (NPR1) is the salicylic acid (SA) receptor, which is critical for stomatal defense.
Qijie Guan +7 more
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Dynamic ubiquitination determines transcriptional activity of the plant immune coactivator NPR1
eLife, 2019 Activation of systemic acquired resistance in plants is associated with transcriptome reprogramming induced by the unstable coactivator NPR1. Immune-induced ubiquitination and proteasomal degradation of NPR1 are thought to facilitate continuous delivery ...
Michael J Skelly +4 more
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NPR1 protein regulates pathogenic and symbiotic interactions between Rhizobium and legumes and non-legumes. [PDF]
PLoS ONE, 2009 BACKGROUND:Legumes are unique in their ability to establish symbiotic interaction with rhizobacteria from Rhizobium genus, which provide them with available nitrogen.
Smadar Peleg-Grossman +4 more
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A novel mode of WRKY1 regulating PR1-mediated immune balance to defend against powdery mildew in apple [PDF]
Molecular HorticulturePowdery mildew (PM), caused by the biotrophic fungus Podospharea leucotricha, poses a significant threat to apple production. Salicylic acid (SA) signaling plays a crucial role in enhancing resistance to biotrophic pathogens. While PR1, a defense protein
Liming Lan +12 more
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Aspirin-responsive gene switch regulating therapeutic protein expression [PDF]
Nature CommunicationsCurrent small-molecule-regulated synthetic gene switches face clinical limitations such as cytotoxicity, long-term side-effects and metabolic disturbances. Here, we describe an advanced synthetic platform inducible by risk-free input medication (ASPIRIN),
Jinbo Huang +5 more
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Genome-wide analysis of NPR1-like genes in citrus species and expression analysis in response to citrus canker (Xanthomonas axonopodis pv. citri) [PDF]
Frontiers in Plant ScienceCitrus fruits, revered for their nutritional value, face significant threats from diseases like citrus canker, particularly impacting global citrus cultivation, notably in Pakistan.
Mobeen Ali +13 more
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NPR1 Translocation from Chloroplast to Nucleus Activates Plant Tolerance to Salt Stress
Antioxidants, 2023 Chloroplasts play crucial roles in biotic and abiotic stress responses, regulated by nuclear gene expression through changes in the cellular redox state.
Soyeon Seo, Yumi Kim, Kyyoung Park
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Pulse, 2023 Introduction: A previous study of 200,000 exome-sequenced UK Biobank participants to test for association of rare coding variants with hypertension implicated two genes at exome-wide significance, DNMT3A and FES.
David Curtis
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