Dynamic ubiquitination determines transcriptional activity of the plant immune coactivator NPR1
eLife, 2019 Activation of systemic acquired resistance in plants is associated with transcriptome reprogramming induced by the unstable coactivator NPR1. Immune-induced ubiquitination and proteasomal degradation of NPR1 are thought to facilitate continuous delivery ...
Michael J Skelly +4 more
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Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone
NatureHeart failure is a leading cause of morbidity and mortality1,2. Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic peptides, which act through their receptor (NPR1) to affect vasodilation, diuresis and natriuresis, lowering venous pressures and relieving venous congestion3-8 ...
Annabel Romero Hernandez +2 more
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Natriuretic peptides as novel regulators of dendritic cells-mediated inflammation [PDF]
Cellular and Molecular Life SciencesNatriuretic Peptides (NPs), including atrial (ANP) and brain (BNP) types, exert pleiotropic effects in regulating immune responses via the Natriuretic Peptide Receptor-1 (NPR1), expressed across various immune cells.
Giorgia Manni +9 more
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A novel mode of WRKY1 regulating PR1-mediated immune balance to defend against powdery mildew in apple [PDF]
Molecular HorticulturePowdery mildew (PM), caused by the biotrophic fungus Podospharea leucotricha, poses a significant threat to apple production. Salicylic acid (SA) signaling plays a crucial role in enhancing resistance to biotrophic pathogens. While PR1, a defense protein
Liming Lan +12 more
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NPR1 Translocation from Chloroplast to Nucleus Activates Plant Tolerance to Salt Stress
Antioxidants, 2023 Chloroplasts play crucial roles in biotic and abiotic stress responses, regulated by nuclear gene expression through changes in the cellular redox state.
Soyeon Seo, Yumi Kim, Kyyoung Park
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Non-Expresser of PR-Genes 1 Positively Regulates Abscisic Acid Signaling in Arabidopsis thaliana
Plants, 2022 The plant hormone, abscisic acid (ABA), is not only important for promoting abiotic stress responses but also plays a versatile and crucial role in plant immunity. The pathogen infection-induced dynamic accumulation of ABA mediates the degradation of non-
Irfan Ullah Khan +7 more
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Non-Coding RNA, 2020 AtR8 lncRNA was previously identified in the flowering plant Arabidopsis thaliana as an abundant Pol III-transcribed long non-coding RNA (lncRNA) of approximately 260 nt.
Shuang Li +5 more
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The cpr5 mutant of Arabidopsis expresses both NPR1-dependent and NPR1-independent resistance. [PDF]
The Plant Cell, 1997 The cpr5 mutant was identified from a screen for constitutive expression of systemic acquired resistance (SAR). This single recessive mutation also leads to spontaneous expression of chlorotic lesions and reduced trichome development. The cpr5 plants were found to be constitutively resistant to two virulent pathogens, Pseudomonas syringae pv maculicola
S A, Bowling +4 more
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Frontiers in Plant Science, 2020 Non-expressor of pathogenesis-related (PR) genes1 (NPR1) is a key transcription coactivator of plant basal immunity and systemic acquired resistance (SAR).
Yezhang Ding +7 more
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NONEXPRESSOR OF PATHOGENESIS‐RELATED PROTEINS1 (NPR1) and some NPR1‐related proteins are sensitive to salicylic acid [PDF]
Molecular Plant Pathology, 2010 SUMMARY NONEXPRESSOR OF PATHOGENESIS‐RELATED PROTEINS1 (NPR1; also known as NIM1) is a master regulator of systemic acquired resistance (SAR). SAR is induced by salicylic acid (SA), leading to the expression of PATHOGENESIS‐RELATED (PR) genes.
Felix, Maier +6 more
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