Results 191 to 200 of about 13,888 (222)

Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone

Nature
Heart failure is a leading cause of morbidity and mortality1,2. Elevated intracardiac pressures and myocyte stretch in heart failure trigger the release of counter-regulatory natriuretic peptides, which act through their receptor (NPR1) to affect vasodilation, diuresis and natriuresis, lowering venous pressures and relieving venous congestion3-8 ...
Vishal Kamat, Ashique Rafique, Jonas Bille Nielsen   +2 more
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NPR1, all things considered

Current Opinion in Plant Biology, 2004
Recent work has shown that the Arabidopsis NPR1 protein not only plays an essential role in salicylic acid (SA)-mediated systemic acquired resistance and rhizobacterium-triggered induced systemic resistance, but also is involved in crosstalk inhibition of jasmonic acid (JA)-mediated defense responses.
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Arabidopsis ein2-1 and npr1-1 Response to Al Stress

Bulletin of Environmental Contamination and Toxicology, 2014
An enhanced Al(3+) tolerance has been observed in ethylene insensitive mutant ein2-1 and salicylic acid insensitive mutant npr1-1 of Arabidopsis. However, we found that the tolerant phenotype of ein2-1 and npr1-1 under Al stress was dependent on NPR and EIN function, respectively, because the double mutant ein2-1/npr1-1 displayed more sensitive to Al ...
Yiyan, Zhang, Qingqing, He, Shiyang, Zhao, Linli, Huang, Lin, Hao   +4 more
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Targeting NPR1: a strategy went viral

Trends in Plant Science
Non-expressor of pathogenesis-related 1 (NPR1) acts as master regulator of plant immunity by promoting salicylic acid (SA) signalling. Some bacterial and fungal pathogens target NPR1 to inhibit SA-mediated immunity. Recently, Zhang et al. and Liu et al.
Dibyendu Ghosh, Supriya Chakraborty
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Molecular cloning and characterization of NPR1 gene from Arachis hypogaea

Molecular Biology Reports, 2014
The NPR1 gene was an important regulator for a plant disease resistance. The cDNA of NPR1 gene was cloned from peanut cultivar Ri Hua 1 by rapid amplification of cDNA ends-polymerase chain reaction (RACE-PCR). The full length cDNA of Arachis hypogaea NPR1 consisted of 2,078 base pairs with a 1,446 bp open-reading frame encoding 481 amino acids.
Qi, Wu, Xiu Zhen, Wang, Yue Yi, Tang, Hong Tao, Yu, Yu Fei, Ding, Chuan, De Yang, Feng Gao, Cui, Jian Cheng, Zhang, Chuan Tang, Wang   +8 more
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Isolation and characterization of the rice NPR1 promoter

Plant Biotechnology Reports, 2009
NPR1 is a positive regulator of systemic acquired resistance in Arabidopsis and rice. Expression of the rice gene OsNPR1 is induced by salicylic acid (SA). To identify the region of the OsNPR1 promoter involved in response to SA, we carried out deletion mutagenesis of the region 1005 bp upstream of the OsNPR1 start codon.
Seon-Hee Hwang, Duk-Ju Hwang
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Elicitor and Fusarium-induced expression of NPR1-like genes in banana

Plant Physiology and Biochemistry, 2008
The non-expressor of pathogenesis-related genes 1 (NPR1) is an essential positive regulator of salicylic acid (SA)-induced pathogenesis-related (PR) gene expression and systemic acquired resistance (SAR). Two novel full length NPR1-like genes; MNPR1A and MNPR1B, were isolated from banana by application of the PCR and rapid amplification of cDNA ends ...
Rosita, Endah, Getu, Beyene, Andrew, Kiggundu, Noelani, van den Berg, Urte, Schlüter, Karl, Kunert, Rachel, Chikwamba   +6 more
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The Arabidopsis NPR1 gene confers broad-spectrum disease resistance in strawberry

Transgenic Research, 2015
Although strawberry is an economically important fruit crop worldwide, production of strawberry is limited by its susceptibility to a wide range of pathogens and the lack of major commercial cultivars with high levels of resistance to multiple pathogens.
Katchen Julliany P, Silva, Asha, Brunings, Natalia A, Peres, Zhonglin, Mou, Kevin M, Folta   +4 more
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NPR1 preferentially binds to the DNA-inactive form of Arabidopsis TGA2

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2008
Systemic acquired resistance (SAR) is triggered by hormone defense cues and is associated with the onset of expression of pathogenesis-related (PR) genes that encode for anti-microbial proteins in plants. In the case of PR-1, transcriptional activation involves promoter-specific recruitment of transcription factors such as TGA2 through a mechanism that
Christopher, Johnson, Amy, Mhatre, Jonathan, Arias   +2 more
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Hydroquinazoline Derivatives as Novel Natriuretic Peptide Receptor 1 (NPR1) Activators

ACS Medicinal Chemistry Letters
This patent highlights hydroquinazoline compounds and their pharmaceutically acceptable salts, as well as compositions and methods of preparation. The compounds in this invention were evaluated for their potency on Natriuretic Peptide Receptor 1 (NPR1), a receptor guanylate cyclase known to play a critical role in lowering blood pressure and blood ...
Xin Zhou, Steven H. Liang
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