Results 101 to 110 of about 4,503 (200)

Human oocyte capacitation culture: Essential step toward hormone‐free assisted reproductive technology

open access: yesReproductive Medicine and Biology, Volume 24, Issue 1, January/December 2025.
The biphasic CAPA‐IVM system promotes oocyte competence acquisition. The use of CAPA‐IVM in clinical studies has set the tone for major progress in the field and is achieving a safer, less expensive, and less emotionally loaded IVF experience, currently validated for PCOS patients.
Johan Smitz   +8 more
wiley   +1 more source

C-type natriuretic peptide analog treatment of craniosynostosis in a Crouzon syndrome mouse model.

open access: yesPLoS ONE, 2018
Activating mutations of fibroblast growth factor receptors (FGFRs) are a major cause of skeletal dysplasias, and thus they are potential targets for pharmaceutical intervention. BMN 111, a C-type natriuretic peptide analog, inhibits FGFR signaling at the
Greg Holmes   +7 more
doaj   +1 more source

Ultrafast and Deep Saliva Proteome Reveals the Dynamic of Human Saliva With Aging by Orbitrap Astral Mass Spectrometer

open access: yesIET Nanobiotechnology, Volume 2025, Issue 1, 2025.
Saliva has already proven to be a prospective diagnostic bioresource for both early disease detection and timely intervention due to its easy accessibility, noninvasiveness, and reproducibility. However, the in‐depth identification of salivary proteins needs to be further improved.
Lingling Jiao   +9 more
wiley   +1 more source

RNAi library screening reveals Gβ1, Casein Kinase 2 and ICAP‐1 as novel regulators of LFA‐1‐mediated T cell polarity and migration

open access: yesImmunology &Cell Biology, Volume 103, Issue 1, Page 73-92, January 2025.
In this study, we screened RNAi libraries, targeting kinases and G protein‐coupled receptors/G protein‐coupled receptor associated proteins for regulators of T‐cell polarity and migration. We identified that Gβ1, casein kinase 2 and ICAP‐1 play key roles in T‐cell adhesion, polarity and migration on ICAM‐1.
Antje Haap‐Hoff   +9 more
wiley   +1 more source

Molecular analysis of sensory axon branching unraveled a cGMP-dependent signaling cascade [PDF]

open access: yes, 2018
Axonal branching is a key process in the establishment of circuit connectivity within the nervous system. Molecular-genetic studies have shown that a specific form of axonal branching - the bifurcation of sensory neurons at the transition zone between ...
Dumoulin, A.   +3 more
core   +2 more sources

Cutis verticis gyrata due to a novel NPR2 variant

open access: yesQJM: An International Journal of Medicine, 2023
J McKenna, P J Morrison
openaire   +4 more sources

Computations for the 16-foot transonic tunnel, NASA, Langley Research Center, revision 1 [PDF]

open access: yes
The equations used by the 16 foot transonic tunnel in the data reduction programs are presented in eight modules. Each module consists of equations necessary to achieve a specific purpose.
Berrier, Bobby L.   +4 more
core   +1 more source

Development of Advanced High Lift Leading Edge Technology for Laminar Flow Wings [PDF]

open access: yes, 2013
This paper describes the Advanced High Lift Leading Edge (AHLLE) task performed by Northrop Grumman Systems Corporation, Aerospace Systems (NGAS) for the NASA Subsonic Fixed Wing project in an effort to develop enabling high-lift technology for laminar ...
Bright, Michelle M.   +3 more
core   +1 more source

Cinderella Strings

open access: yes, 1993
We investigate recent claims concerning a new class of cosmic string solutions in the Weinberg-Salam model. They have the general form of previously discussed semi-local and electroweak strings, but are modified by the presence of a non-zero W-condensate
A. Achúcarro   +12 more
core   +1 more source

A tudor domain protein SPINDLIN1 interacts with the mRNA-binding protein SERBP1 and is involved in mouse oocyte meiotic resumption [PDF]

open access: yes, 2013
Mammalian oocytes are arrested at prophase I of meiosis, and resume meiosis prior to ovulation. Coordination of meiotic arrest and resumption is partly dependent on the post-transcriptional regulation of maternal transcripts.
A Goncalves Kde   +43 more
core   +3 more sources

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