A novel loss-of-function mutation in Npr2 clarifies primary role in female reproduction and reveals a potential therapy for acromesomelic dysplasia, Maroteaux type [PDF]
Krista A. Geister+8 more
openalex +1 more source
GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing
Sensory axon T-like branching (bifurcation) in neurons from dorsal root ganglia and cranial sensory ganglia depends on the molecular signaling cascade involving the secreted factor C-type natriuretic peptide, the natriuretic peptide receptor guanylyl ...
Steffen Wolter+10 more
doaj +1 more source
Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a role for C-type natriuretic peptide [PDF]
Iain Thompson+15 more
openalex +1 more source
the receptor guanylyl cyclase npr2 regulates the bifurcation of cranial sensory axons
Die axonale Verzweigung ist ein wichtiger Mechanismus, um die komplexen Verschaltungen des Nervensystems zu bilden. Je nach ihrer Funktion können sich Axone weitläufig verzweigen, um die Informationen an ihre verschiedenen Ziele zu senden und ein einzigartiges Muster der Verschaltung zu etablieren. Allerdings sind die Signalmechanismen, die die axonale
openaire +2 more sources
A series of solvent-stabilized ionic liquid fluorides were prepared, [EMIM]F.nCH3COOH n = 1. 0, 1.6, 2.1, 2.4, and 3.2, either via exchange from the chloride salt using KF or AgF, or by neutralization of the hydroxide salt using HF.
Owen J. Curnow+2 more
doaj +1 more source
Protein pocket and ligand shape comparison and its application in virtual screening [PDF]
Understanding molecular recognition is one major requirement for drug discovery and design. Physicochemical and shape complementarity between two binding partners is the driving force during complex formation.
Michielin, Olivier+6 more
core
High-Reynolds Number Circulation Control Testing in the National Transonic Facility [PDF]
A new capability to test active flow control concepts and propulsion simulations at high Reynolds numbers in the National Transonic Facility at the NASA Langley Research Center is being developed.
Chan, David T.+3 more
core +1 more source
Simple Scaling of Multi-Stream Jet Plumes for Aeroacoustic Modeling [PDF]
When creating simplified, semi-empirical models for the noise of simple single-stream jets near surfaces it has proven useful to be able to generalize the geometry of the jet plume. Having a model that collapses the mean and turbulent velocity fields for
Bridges, James
core +1 more source
A novel nonsense mutation in NPR2 gene causing Acromesomelic dysplasia, type Maroteaux in a consanguineous family in Southern Punjab (Pakistan) [PDF]
Saima Mustafa+5 more
openalex +1 more source
Numerical simulation of nanopulse penetration of biological matter using the z -transform [PDF]
Short duration, fast rise time ultra-wide-band (UWB) electromagnetic pulses (“nanopulses”) are generated by numerous electronic devices in use today.
Su, Shengjun
core +1 more source