Results 191 to 200 of about 4,503 (200)

Phenotypic and genotypic insights into concurrent tertiary trisomy for 9p and 18p. [PDF]

Mol Cytogenet
Wright CA, Scheuerle AE, Wilson K, García R, Koduru P.   +4 more
europepmc   +1 more source

Deficiencies in corin and atrial natriuretic peptide-mediated signaling impair endochondral ossification in bone development. [PDF]

Commun Biol
Zhou Z, Mao X, Jiang C, Li W, Zhou T, Liu M, Sun S, Wang M, Dong N, Wu Q, Zhou H.   +10 more
europepmc   +1 more source

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Expression and localization of Npr2 in mouse oocytes and pre-implantation embryos

Biotechnic & Histochemistry, 2019
We investigated the expression and localization of natriuretic peptide receptor 2 (Npr2) in mouse oocytes and pre-implantation embryos. Immunocytochemistry and quantitative real-time polymerase chain reaction (qRT-PCR) were performed on mouse oocytes and embryos at different developmental stages.
W Fu, L Li, X Cao, Lei Yang, Lanjie Lei, H Xi   +5 more
openaire   +3 more sources

Nppc/Npr2/cGMP signaling cascade maintains oocyte developmental capacity

Cellular and Molecular Biology, 2019
The follicle must fulfill the following criteria if it is to survive the period between early embryonic life and the luteinizing hormone (LH) peak. It should (i) be surrounded by pregranulosa cells; (ii) complete the first meiotic division and become dormant; and (iii) continue metabolism during the dormant stage.
Nilufer Celik, Onder Celik, Seyda Yavuzkir, Suleyman Aydin, Ibrahim Sahin, Kader Ugur, Iptisam Ipek Muderris, Safak Hatirnaz, Meltem Yardim, Sudenaz Celik   +9 more
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A NOVEL MUTATION IN NPR2 GENE IN A PATIENT WITH ACROMESOMELIC DYSPLASIA, MAROTEAUX TYPE.

Genetic counseling (Geneva, Switzerland), 2015
Acromesomelic dysplasia, Maroteaux type (AMDM) is a rare autosomal recessive disease characterized by disproportionate shortening of skeletal elements, predominantly affecting the middle segments (forearms and forelegs) and distal segments (hands and feet) of appendicular skeleton.
Yakut, T., Gulten, T., Sahinturk, SERDAR, Ture, M., Gorukmez, O., Topak, A., Gorukmez, O., Sag, S. Ozemri   +7 more
openaire   +2 more sources

Suppression of Npr1, not Npr2 gene function induces hypertrophic growth in H9c2 cells in vitro

Biochemical and Biophysical Research Communications, 2017
Npr1 gene (coding for NPR-A) and Npr2 gene (coding for NPR-B) are identified as intrinsic anti-hypertrophic genes that opposes abnormal cardiac remodeling. However, the functional role of Npr1 and Npr2 genes during cardiac hypertrophic growth is not well understood.
Elangovan Vellaichamy, Senthamizharasi Manivasagam   +1 more
openaire   +2 more sources

NPR2 and Acromesomelic Dysplasia, Type Maroteaux

2008
Abstract A signaling pathway that is active during endochondral ossi2cation, involving C-type natriuretic peptide [CNP, gene name natriuretic peptide precursor C (NPPC)] and the natriuretic peptide receptors 2 and 3 (NPR2, NPR3) is essential for normal skeletal growth.
Matthew L Warman, Robert C Olney
openaire   +1 more source

NPR2 Heterozigot Mutasyonuna Bağlı Boy Kısalığı

2020
GirişNPR2 geni, C tipi natriüretik peptit bağlayan üç membran reseptöründen en yüksek afiniteye sahip olanreseptör NPR B’yi kodlar. Homozigot mutasyonları ciddi boy kısalığı ve vücut orantısızlığı olan MaroteauxTip Akromesomelik Displaziye (AMDM) neden olur.
Bideci, Aysun, Küpçü, Zekiye, Cinaz, Peyami, Perçin, Ferda Emriye, Kayhan, Gülsüm, Döğer, Esra, Çamurdan, Mahmut Orhun   +6 more
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NPR2 (Natriuretic Peptide Receptor 2)

2018
openaire   +1 more source