Results 61 to 70 of about 5,736 (234)

The First Turkish Family with Skeletal Abnormality and Novel NPR2 Gene Mutation

Turkiye Klinikleri Journal of Case Reports, 2020
Nadide Cemre Randa
openalex   +2 more sources

Protective Effects of C-Type Natriuretic Peptide on Linear Growth and Articular Cartilage Integrity in a Mouse Model of Inflammatory Arthritis [PDF]

, 2014
Objective: The C-type natriuretic peptide (CNP) signaling pathway is a major contributor to postnatal skeletal growth in humans. This study was undertaken to investigate whether CNP signaling could prevent growth delay and cartilage damage in an animal ...
Bartels, Cynthia F, Bükülmez, Hülya, Haqqi, Tariq M, Khan, Fozia, Murakami, Shunichi, Ortiz-Lopez, Adriana, Sattar, Abdus, Warman, Matthew L   +7 more
core   +1 more source

Cyclic AMP links luteinizing hormone signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in ovarian follicles†

Biology of Reproduction, 2021
Summary sentence Cyclic AMP elevation links luteinizing hormone receptor signaling to dephosphorylation and inactivation of the NPR2 guanylyl cyclase in preovulatory mouse follicles.
J. Egbert, J. Robinson, T. Uliasz, L. Potter, L. Jaffe   +4 more
semanticscholar   +1 more source

Oocyte maturation and quality: role of cyclic nucleotides [PDF]

, 2016
Advance Publication first posted online on 15 July 2016 - Accepted manuscriptThe cyclic nucleotides, cAMP and cGMP, are the key molecules controlling mammalian oocyte meiosis.
De Vos, M., Gilchrist, R., Luciano, A., Richani, D., Richard, F., Smitz, J., Sugimura, S., Thompson, J., Wang, X., Zeng, H.   +9 more
core   +1 more source

C-type natriuretic peptide facilitates autonomic Ca2+ entry in growth plate chondrocytes for stimulating bone growth

eLife, 2022
The growth plates are cartilage tissues found at both ends of developing bones, and vital proliferation and differentiation of growth plate chondrocytes are primarily responsible for bone growth. C-type natriuretic peptide (CNP) stimulates bone growth by
Yuu Miyazaki, Atsuhiko Ichimura, Ryo Kitayama, Naoki Okamoto, Tomoki Yasue, Feng Liu, Takaaki Kawabe, Hiroki Nagatomo, Yohei Ueda, Ichiro Yamauchi, Takuro Hakata, Kazumasa Nakao, Sho Kakizawa, Miyuki Nishi, Yasuo Mori, Haruhiko Akiyama, Kazuwa Nakao, Hiroshi Takeshima   +17 more
doaj   +1 more source

Genetics of Growth Disorders-Which Patients Require Genetic Testing? [PDF]

, 2019
The second 360° European Meeting on Growth Hormone Disorders, held in Barcelona, Spain, in June 2017, included a session entitled Pragmatism vs. Curiosity in Genetic Diagnosis of Growth Disorders, which examined current concepts of genetics and growth in
Argente, J, Lehwalder, D, Pfäffle, R, Tatton-Brown, K   +3 more
core   +1 more source

HeterozygousNPR2Mutations Cause Disproportionate Short Stature, Similar to Léri-Weill Dyschondrosteosis [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2015
SHOX mutations have been detected in approximately 70% of Léri-Weill dyschondrosteosis (LWD) and approximately 2.5% of idiopathic short stature (ISS) cases, suggesting the implication of other genes or loci. The recent identification of NPR2 mutations in ISS suggested that NPR2 mutations may also be involved in disproportionate short stature.The ...
Alfonso, Hisado-Oliva, Ana I, Garre-Vázquez, Fabiola, Santaolalla-Caballero, Alberta, Belinchón, Ana C, Barreda-Bonis, Gabriela A, Vasques, Joaquin, Ramirez, Cristina, Luzuriaga, Gianni, Carlone, Isabel, González-Casado, Sara, Benito-Sanz, Alexander A, Jorge, Angel, Campos-Barros, Karen E, Heath   +13 more
openaire   +2 more sources

Macrophage colony-stimulating factor (M-CSF) is an intermediate in the process of luteinizing hormone-induced decrease in natriuretic peptide receptor 2 (NPR2) and resumption of oocyte meiosis

Journal of Ovarian Research, 2017
Background Luteinizing hormone (LH) regulation of the ligand, natriuretic peptide precursor type C, and its receptor, natriuretic peptide receptor 2 (NPR2), is critical for oocyte maturation; however, the mechanism is not fully understood.
Wenchao Sun, Chang Liu, Ying Feng, Guangchao Zhuo, Wenjing Zhou, Xiaoyang Fei, Zhifen Zhang   +6 more
doaj   +1 more source

De novo c.2455C>T mutation of NPR2 gene in a fetus with shortened long bones and a ventricular septal defect conceived by a mother with a fragile site at 16q22.1 and a father with a rare heterochromatic variant of chromosome 4 from Vietnam

Molecular Genetics & Genomic Medicine, 2021
Background A heterozygous natriuretic peptide receptor 2 (NPR2) gene c.2455C>T mutation was identified as a cause of familial idiopathic short stature (ISS).
Thi Minh Thi Ha, Tran Thao Nguyen Nguyen, Thi Mai Ngan Nguyen, Huu Nguyen Nguyen   +3 more
doaj   +1 more source

New mechanism underlying IL-31-induced atopic dermatitis [PDF]

, 2018
LBK
Buddenkotte, Joerg, Buhl, Timo, Feld, Micha, Fischer, Michael, Ghetti, Andre, Meng, Jianghui, Miller, Paul, Moriyama, Masaki, Reeh, Peter W., Shan, Chunxu, Steinhoff, Martin, Szöllősi, Attila Gábor, Wang, Jiafu, Zhang, Jingming   +13 more
core   +1 more source