Results 61 to 70 of about 4,503 (200)

Heterozygous Mutations in Natriuretic Peptide Receptor-B (NPR2) Gene as a Cause of Short Stature [PDF]

Human Mutation, 2015
Based on the observation of reduced stature in relatives of patients with acromesomelic dysplasia, Maroteaux type (AMDM), caused by homozygous or compound heterozygous mutations in natriuretic peptide receptor-B gene (NPR2), it has been suggested that heterozygous mutations in this gene could be responsible for the growth impairment observed in some ...
Sophie R. Wang, Christina M. Jacobsen, Heather Carmichael, Aaron B. Edmund, Jerid W. Robinson, Robert C. Olney, Timothy C. Miller, Jennifer Moon, Verónica Mericq, Lincoln R. Potter, Matthew L. Warman, Joel N. Hirschhorn, Andrew Dauber   +12 more
openalex   +5 more sources

Molecular Mechanism of Blood Pressure Regulation through the Atrial Natriuretic Peptide

Biology, 2022
Natriuretic peptides, including atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide (CNP), have cardioprotective effects and regulate blood pressure in mammals.
Takeshi Tokudome, Kentaro Otani
doaj   +1 more source

Method for High Accuracy Multiplicity Correlation Measurements

, 2014
Multiplicity correlation measurements provide insight into the dynamics of high energy collisions. Models describing these collisions need these correlation measurements to tune the strengths of the underlying QCD processes which influence all ...
Gulbrandsen, K., Soegaard, C.
core   +1 more source

Reactive Palladium Carbenes: Migratory Insertion and Other Carbene-Hydrocarbyl Coupling Reactions on Well-Defined Systems [PDF]

, 2018
Producción CientíficaPalladium complexes with carbene ligands are among the best known and more extensively used catalysts. Those carbenes are usually NHC or N,N-disubstituted derivatives and their use relies on the robust nature of the carbene ligands ...
Albéniz Jiménez, Ana Carmen
core   +2 more sources

Retinal degeneration protein 3 controls membrane guanylate cyclase activities in brain tissue

Frontiers in Molecular Neuroscience, 2022
The retinal degeneration protein RD3 is involved in regulatory processes of photoreceptor cells. Among its main functions is the inhibition of photoreceptor specific membrane guanylate cyclases during trafficking from the inner segment to their final ...
Yaoyu Chen, Yaoyu Chen, Anja U. Bräuer, Anja U. Bräuer, Karl-Wilhelm Koch, Karl-Wilhelm Koch   +5 more
doaj   +1 more source

Effect of C-Type Natriuretic Peptide on Maturation and Developmental Competence of Goat Oocytes Matured In Vitro. [PDF]

PLoS ONE, 2015
The developmental competence of oocytes during in vitro maturation (IVM) is compromised due to asynchronous nuclear and cytoplasmic maturation. To improve IVM efficiency, a pre-maturation culture or two-step maturation strategy has been established ...
Junhong Zhang, Qiang Wei, Jiao Cai, Xiaoe Zhao, Baohua Ma   +4 more
doaj   +1 more source

Phosphodiesterase 3 inhibitors boost bone outgrowth

British Journal of Pharmacology, EarlyView.
Background and Purpose C‐type natriuretic peptide (CNP) stimulates skeletal growth by acting on the growth plates of long bones, and a CNP variant is clinically used for achondroplasia treatment. We previously reported that CNP stimulates the autonomic Ca2+ influx mediated by TRPM7 channels in growth plate chondrocytes to facilitate extracellular ...
Takaaki Kawabe, Atsuhiko Ichimura, Tomoki Yasue, Jianhong Li, Haruki Ishikawa, Ga Eun Kim, Hiroki Nagatomo, Naoto Minamino, Yohei Ueda, Hiromu Ito, Miyuki Nishi, Hiroshi Takeshima   +11 more
wiley   +1 more source

The Absence of Sensory Axon Bifurcation Affects Nociception and Termination Fields of Afferents in the Spinal Cord

Frontiers in Molecular Neuroscience, 2018
A cGMP signaling cascade composed of C-type natriuretic peptide, the guanylyl cyclase receptor Npr2 and cGMP-dependent protein kinase I (cGKI) controls the bifurcation of sensory axons upon entering the spinal cord during embryonic development.
Philip Tröster, Julia Haseleu, Jonas Petersen, Jonas Petersen, Oliver Drees, Achim Schmidtko, Achim Schmidtko, Frederick Schwaller, Gary R. Lewin, Gohar Ter-Avetisyan, York Winter, Stefanie Peters, Susanne Feil, Robert Feil, Fritz G. Rathjen, Hannes Schmidt   +15 more
doaj   +1 more source

Сlinical and Radiological Characteristics of Two Patients with Acromesomelic Dysplasia Maroteaux Type with New Mutation in the NRP2 Gene

Travmatologiâ i Ortopediâ Rossii, 2020
Relevance. Acromezomelic dysplasia Maroteaux type (AMDM) is a rare variant of autosomal recessive skeletal disorder. The disease is caused by mutations in the NPR2 gene, coding the protein product which is one of the main regulators of endochondral ...
T. V. Markova, V. M. Kenis, O. L. Mironovich, O. A. Shchagina, T. S. Nagornova, E. V. Melchenko, E. L. Dadali   +6 more
doaj   +1 more source

Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase†. [PDF]

Biol Reprod, 2023
Abstract In response to luteinizing hormone (LH), multiple proteins in rat and mouse granulosa cells are rapidly dephosphorylated, but the responsible phosphatases remain to be identified. Because the phosphorylation state of phosphatases can regulate their interaction with substrates, we searched for phosphatases that might function in ...
Egbert JR, Silbern I, Uliasz TF, Lowther KM, Yee SP, Urlaub H, Jaffe LA.   +6 more
europepmc   +5 more sources