Results 31 to 40 of about 288,885 (258)

Improving of the G2C Payment Mechanism as the Part of the Development of the Social Treasury Project Using the Russian National Payment System

open access: yesУправленческие науки, 2023
The purpose of the study is to consider the possibility of improving the G2C payment mechanism in the context of the digital transformation of the social sphere, as well as to develop a methodological concept for a model for implementing a centralized ...
S. A. Tomilina, M. L. Dorofeev
doaj   +1 more source

Today@NPS / July 2016 [PDF]

open access: yes, 2016
Today@NPS showcases some of the speakers, conferences, experiments, lectures and other events that take place at the Naval Postgraduate SchoolContents: July 1, 2016: NPS Leadership Share Life Primers with Summer STEM Interns; July 5, 2016: Summer Quarter
NPS Public Affairs Office
core   +1 more source

NPS MedicineWise: 20 years of change

open access: yesJournal of Pharmaceutical Policy and Practice, 2018
The cost and potential harms of medicines and other health technologies are issues of concern for governments and third party payers of health care. Various means have been demonstrated to promote appropriate evidence-based use of these technologies as a
Lynn Maria Weekes   +3 more
doaj   +1 more source

Early fall and late winter diets of migratory caribou in northwest Alaska

open access: yesRangifer, 2018
Lichens are the primary winter forage for large herds of migratory caribou (Rangifer tarandus). Caribou select for lichens more than they are available across the landscape and they generally avoid, during winter, habitat that has been burned by ...
Kyle Joly, Matthew D. Cameron
doaj   +1 more source

Probing the ionotropic activity of glutamate GluD2 receptor in HEK cells with genetically-engineered photopharmacology

open access: yeseLife, 2020
Glutamate delta (GluD) receptors belong to the ionotropic glutamate receptor family, yet they don’t bind glutamate and are considered orphan. Progress in defining the ion channel function of GluDs in neurons has been hindered by a lack of pharmacological
Damien Lemoine   +7 more
doaj   +1 more source

Alternative polyadenylation produces multiple 3’ untranslated regions of odorant receptor mRNAs in mouse olfactory sensory neurons

open access: yesBMC Genomics, 2019
Background Odorant receptor genes constitute the largest gene family in mammalian genomes and this family has been extensively studied in several species, but to date far less attention has been paid to the characterization of their mRNA 3′ untranslated ...
Mohamed Doulazmi   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Social interactions impact on the dopaminergic system and drive individuality

open access: yesNature Communications, 2018
Individual animals differ in behavioral traits, but the mechanisms underlying individuation are unclear. Here, the authors show that mice living in a ‘city’ develop individual behavior differences, associated with changes in dopamine cell firing, that ...
N. Torquet   +15 more
doaj   +1 more source

Analyzing the Open/Deep Web to Better Understand the New/Novel Psychoactive Substances (NPS) Scenarios: Suggestions from CASSANDRA and NPS.Finder Research Projects

open access: yesBrain Sciences, 2020
New/novel psychoactive substances (NPS) are defined as new narcotic/psychotropic drugs which are not controlled by the United Nations’ 1961 Narcotic Drugs/1971 Psychotropic Substances conventions, but which may pose a public health threat [...]
Fabrizio Schifano
doaj   +1 more source

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