Results 241 to 250 of about 119,560 (316)

AI‐assisted design of a VEGFR2 agonistic peptide that promotes angiogenesis and wound repair

open access: yesProtein Science, Volume 35, Issue 4, April 2026.
Abstract Vascular endothelial growth factor (VEGF) serves as a principal regulator of neovascularization and is essential for vascular regeneration. In this study, we identified and evaluated VEGF Mimetic Peptide3 (VMP3), a novel synthetic peptide developed as a potential VEGFR‐2/VEGF‐A modulator.
Farzana Yasmeen   +7 more
wiley   +1 more source

Human Citrate Synthase Post‐Translational Modification Mimics and Molecular Dynamic Simulations Demonstrate Attenuation of Acetyl‐CoA/CoA Binding

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 94, Issue 4, Page 883-892, April 2026.
ABSTRACT Human citrate synthase (hCS) is a mitochondrial enzyme that catalyzes the aldol condensation of acetyl coenzyme A (AcCoA) to oxaloacetate to form citrate in the TCA cycle. CS activity is important for aerobic exercise performance and basic metabolic function as a housekeeping enzyme.
Noah Shackelford   +3 more
wiley   +1 more source

Characteristics of fungicide resistance in Asian soybean rust (Phakopsora pachyrhizi) in Paraguay for 2022–2023: insights from genetic mutations and molecular dynamics simulations

open access: yesPest Management Science, Volume 82, Issue 4, Page 3116-3126, April 2026.
Phakopsora pachyrhizi in Paraguay showed diverse resistance to DMI, SDHI, and QoI fungicides at both regional and intra‐field levels, likely driven by target mutation genes. Abstract BACKGROUND Phakopsora pachyrhizi, the causative agent of Asian soybean rust, poses a major threat to soybean production in South America. The rising incidence of fungicide
Ryusuke Hagihara   +5 more
wiley   +1 more source

Exceptionally Elongated Strike‐Slip Rupture Caused by the 2025 MW 7.8 Myanmar Earthquake

open access: yesGeophysical Research Letters, Volume 53, Issue 6, 28 March 2026.
Abstract The interplay between fault geometry and rupture behavior remains poorly understood. The 2025 Myanmar earthquake ruptured the Sagaing fault, a major continental strike‐slip fault with simple geometry. We integrated geodetic and teleseismic observations to investigate its rupture process through finite‐fault kinematic inversions and back ...
Quanshu Zhao   +7 more
wiley   +1 more source

Unraveling Charging and Discharging Processes in Organic Radical‐Based Electrodes: A Hierarchical Molecular and Quantum Mechanical Approach

open access: yesChemSusChem, Volume 19, Issue 6, 27 March 2026.
Charge transfer processes are investigated in p‐type organic electrode materials utilizing stable organic radicals incorporated in a conjugated backbone. Molecular dynamics simulations and time‐dependent density functional theory calculations allow us to evaluate charge transfer states as well as the underlying structure–property relationships. Organic
Clara Zens   +3 more
wiley   +1 more source

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