Results 41 to 50 of about 52,027 (252)

Structural and Dynamic Properties of Lipid‐Coated Gold Nanoparticles

Advanced Materials Interfaces, EarlyView.
Atomistic molecular dynamics simulations reveal how lipid chemistry governs the behavior of coatings on the surface of a gold nanoparticle. Variations in headgroup charge and acyl‐chain saturation produce distinct monolayer‐like lipid organization, ranging from compact, ordered coatings to extended, dynamic shells. These findings establish a foundation
Kalpani A. Mirihana, Rashad Kariuki, Charlotte E. Conn, Aaron Elbourne, Andrew J. Christofferson   +4 more
wiley   +1 more source

Youths Interests in the Biosphere and Sensitivity to Nuclear Power Technology in the UAE: With Discussions on Open Innovation and Technological Convergence in Energy and Water Sectors

Journal of Open Innovation: Technology, Market and Complexity, 2020
Nuclear power technology (NPT) perception and acceptance have globally emerged as the most critical questions for the successful integration of NPT into any national energy mix.
Ibrahim Niankara
doaj   +1 more source

Supporting translation of research evidence into practice—the use of Normalisation Process Theory to assess and inform implementation within randomised controlled trials: a systematic review

Implementation Science, 2023
Background The status of randomised controlled trials (RCTs) as the ‘gold standard’ for evaluating efficacy in healthcare interventions is increasingly debated among the research community, due to often insufficient consideration for implementation ...
Allison Williams, Laura Lennox, Matthew Harris, Grazia Antonacci   +3 more
doaj   +1 more source

Rethinking the NPT

, 1995
The Treaty on the Nonproliferation of Nuclear Weapons (NPT), with over 160 parties, is the most widely adhered to arms control treaty in history, but it has been criticized throughout its existence.
Pilat, J. F.
core   +1 more source

Atomistic Insights into Gradient Architecture Driven Strengthening in Additively Manufactured Cu–Ni Stepwise Graded Structures

Advanced Materials Interfaces, EarlyView.
Atomistic simulations reveal the interlayer mechanics of additively manufactured materials, showing how build direction and layer interfaces govern diffusion, defect evolution, and mechanical strength. Distinct anisotropic behavior arises from interface‐controlled deformation and dislocation activity, establishing critical links between microstructural
Rohit Singh, Jinoop Arackal Narayanan
wiley   +1 more source

The Future of NPT

, 2005
The recently concluded 2005 Review Conference (RevCon) of the nuclear NonProliferation Treaty (NPT) revealed what was widely expected but nevertheless deeply troubling: that the regime was in a fragile state, marked by internal incompatibilities and ...
Hanson, M.
core   +1 more source

Deep Contrastive Learning for High‐Throughput Prediction of Drug Resistance Mutations from Sequences

Advanced Science, EarlyView.
This study presents DeepMutDTA, a deep learning framework aimed at predicting mutation‐induced changes in protein‐drug interactions and prioritizing variants potentially linked to drug resistance. Trained on large‐scale data, it incorporates SimSiam‐MuTF, a label‐aware contrastive fine‐tuning strategy that encourages separation between WT and MT ...
Xiaowen Hu, Pan Zhang, Shangqian Wu, Hao Sun, Minwei Li, Sophia Tsoka, Zizhang Sheng, Lei Deng   +7 more
wiley   +1 more source

Translational framework for implementation evaluation and research: a normalisation process theory coding manual for qualitative research and instrument development

Implementation Science, 2022
Background Normalisation Process Theory (NPT) is frequently used to inform qualitative research that aims to explain and evaluate processes that shape late-stage translation of innovations in the organisation and delivery of healthcare.
Carl R. May, Bianca Albers, Mike Bracher, Tracy L. Finch, Anthony Gilbert, Melissa Girling, Kathryn Greenwood, Anne MacFarlane, Frances S. Mair, Christine M. May, Elizabeth Murray, Sebastian Potthoff, Tim Rapley   +12 more
doaj   +1 more source

Normalisation Process Theory (NPT): Constructs and explanations.

, 2023
Normalisation Process Theory (NPT): Constructs and explanations.
Mohammad J. Alhawajreh (17583199), Audrey S. Paterson (17583202), William J. Jackson (17583205)   +2 more
core   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source