Results 71 to 80 of about 52,027 (252)

Comparison between nocturnal penile tumescence (NPT) and artificial full erection [PDF]

open access: yes, 1988
Recording of nocturnal penile tumescence (NPT) is useful for the objective diagnosis of impotence. However, criteria for evaluating obtained results have not been firmly established. Since the increase in the penile circumference varies among individuals,
佐藤, 嘉一   +4 more
core  

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

open access: yesAdvanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li   +9 more
wiley   +1 more source

MCIS CNS NPT Briefing Book (2008 Edition)

open access: yes, 2008
The NPT Briefing Book (2008 Edition) is comprised of two parts. Part I contains introductory background information on the nuclear non-proliferation regime and nuclear energy issues, as well as summaries of the review process to date.
Stoddart, Kristan   +2 more
core   +1 more source

Using Normalization Process Theory in feasibility studies and process evaluations of complex healthcare interventions: a systematic review

open access: yesImplementation Science, 2018
Background Normalization Process Theory (NPT) identifies, characterises and explains key mechanisms that promote and inhibit the implementation, embedding and integration of new health techniques, technologies and other complex interventions.
Carl R. May   +9 more
doaj   +1 more source

The EU's performance in the 2015 NPT Review Conference: What went wrong

open access: yes, 2015
This article presents a performance analysis of the European Union (EU) during the 2015 Nuclear Non-Proliferation Treaty (NPT) Review Conference. Detailing what went wrong for the EU across three levels of performance analysis, the article goes on to ...
Dee, Megan
core  

Molecular Dynamics‐Guided Sterol Engineering of mRNA‐Lipid Nanoparticles Reprograms Biodistribution and Enhances Spleen‐Selective Immunity

open access: yesAdvanced Science, EarlyView.
Sterol engineering enables precise control of mRNA lipid nanoparticles by tuning membrane organization. Replacing cholesterol with bile acid‐derived sterols redirects protein expression from the liver to the spleen. Notably, CA‐20 LNP enhances antigen‐specific immune responses while exhibiting a favorable safety profile, highlighting sterols as a ...
Sanghyuk Jeon   +27 more
wiley   +1 more source

NPT briefing book - April 2007 edition

open access: yes, 2007
The NPT Briefing Book (April 2007 Edition) is comprised of two parts. Part I contains introductory background information on the nuclear non-proliferation regime and nuclear energy issues, as well as summaries of the review process to date.

core   +1 more source

It’s Time to Scrap the NPT

open access: yes, 2005
Due to persisting demand-side factors and crumbling supply-side controls, the nuclear Non-Proliferation Treaty (NPT) will probably be unable to prevent a likely proliferation rate of one or two additional nuclear weapons states per decade into the ...
Wesley, Michael
core   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

open access: yesAdvanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang   +11 more
wiley   +1 more source

Effect of Negative Pressure Therapy on the Inflammatory Response of the Intestinal Microenvironment in a Porcine Septic Model

open access: yesMediators of Inflammation, 2015
In a swine model of ischemia/reperfusion injury coupled with sepsis, we have previously shown attenuation of secondary organ injury and decreased mortality with negative pressure therapy (NPT).
Kenneth C. Norbury, Mary Pat Moyer
doaj   +1 more source

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