Results 61 to 70 of about 233,711 (284)
Optimizing Diagnostic Accuracy of Clinical Red Flags in RASopathies
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT RASopathies are a group of genetic disorders caused by pathogenic variants in the RAS‐mitogen‐activated protein kinase (RAS–MAPK) signaling pathway, often presenting with congenital heart defects, craniofacial dysmorphisms, and developmental delays. To assess the diagnostic yield of genetic testing in patients with suspected RASopathies and to
Emanuele Bobbio +16 more
wiley +1 more source
European Journal of Entomology, 2001 As part of a search for natural enemies of the gypsy moth (Lymantria dispar), virus-infected samples were collected near Toulouse, France. Light and electron microscope studies confirmed that the French strain is a multinucleocapsid nuclear polyhedrosis ...
Neelam NARANG +4 more
doaj +1 more source
Frequency and significance of Ras, Tert promoter, and Braf mutations in cytologically indeterminate thyroid nodules: A monocentric case series at a tertiary-level Endocrinology unit [PDF]
, 2017 PurposeThe management of thyroid nodules of indeterminate cytology is controversial. Our study aimed to establish the frequency and significance of H-,K-,N-RAS, TERT promoter, and BRAF gene mutations in thyroid nodes of indeterminate cytology and to ...
Barollo, Susi +13 more
core +2 more sources
Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics
Annals of Neurology, EarlyView.Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino +23 more
wiley +1 more source
Uncertainty and Human Capital Decisions: Traditional Valuation Methods and Real Options Logic [PDF]
, 2007 As the importance of human capital increases in organizations, so does the need to develop more sophisticated financial valuation models. This paper reviews some of the major traditional financial decision making models used in costing employment mode ...
Badders, Brett +2 more
core +1 more source
Annals of Neurology, EarlyView.Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim +14 more
wiley +1 more source
, 2014 Net Present Value is a deceptively simple prescription that has dominated academic advice. Discount all expected cash flows at a risk adjusted discount rate and if the result is positive, invest, otherwise do not invest. It is still possible to read the following in textbooks: “NPV considers all of the costs and benefits of each investment opportunity”
Fox, RP, Roddy, EM, Swientozielskyj, S
openaire
Firm Projects, NPV and Risk [PDF]
, 2005 LaTeX, econophysics, firm projects, NPV, risk, normal distribution, a few typographical errors ...
Jana Hudakova, Ondrej Hudak
openaire +2 more sources
An equitable approach to the payment scheduling problem in project management [PDF]
, 2000 This study reports on a new approach to the payment scheduling problem. In this approach, the amount and timing of the payments made by the client and received by the contractor are determined so as to achieve an equitable solution.
Cebelli, Serkan +2 more
core +1 more source
Annals of Neurology, EarlyView.Objective This study aimed to compare positron emission tomography (PET) and plasma‐based temporal modeling of amyloid and tau biomarkers in Alzheimer's disease. Methods Longitudinal amyloid PET (n = 1,097, mean age ± SD = 72.5 ± 7.38 year, 51.4% male), 18F‐flortaucipir tau‐PET (n = 230, 74.3 ± 7.18 year, 52.2% female), and Fujirebio Lumipulse plasma p‐
Christopher A. Brown +14 more
wiley +1 more source