Results 41 to 50 of about 103,009 (233)
Advanced Science, EarlyView.The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang +12 more
wiley +1 more source
The National Security Agency\u27s Domestic Spying Program: Framing the Debate [PDF]
, 2006 On Friday, December 16, 2005, the New York Times reported that President George W. Bush had secretly authorized the National Security Agency (NSA) to conduct warrantless surveillance of Americans\u27 telephone and e-mail communications as part of an ...
Cole, David, Lederman, Martin S.
core +1 more source
Advanced Science, EarlyView.The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu +9 more
wiley +1 more source
Brazilian version of the Nottingham Sensory Assessment: validity, agreement and reliability [PDF]
, 2010 OBJETIVO: Verificar a concordância inter e intraexaminador, validade construtiva e consistência interna da versão brasileira do instrumento Nottingham Sensory Assessment para hemiparéticos após acidente vascular encefálico (AVE).
LIMA, Daniela H. F. +5 more
core +1 more source
Advanced Science, EarlyView.The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi +13 more
wiley +1 more source
Open Physics, 2018 In this article, the generalized shallow water wave (GSWW) equation is studied from the perspective of one dimensional optimal systems and their conservation laws (Cls).
Baleanu Dumitru +3 more
doaj +1 more source
Why the NSA Data Seizures Are Unconstitutional [PDF]
, 2015 Due to the unauthorized leaks of classified information, we have come to learn that the National Security Agency (NSA), an executive branch arm of the U.S. military, has established several data collection programs. In this article, I am not going to get
Barnett, Randy E
core +1 more source
Equivalence of the Traditional and Non-Standard Definitions of Concepts from Real Analysis
, 2014 ACL2(r) is a variant of ACL2 that supports the irrational real and complex numbers. Its logical foundation is based on internal set theory (IST), an axiomatic formalization of non-standard analysis (NSA). Familiar ideas from analysis, such as continuity,
Cowles, John, Gamboa, Ruben
core +2 more sources
One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy
Advanced Science, EarlyView.This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu +8 more
wiley +1 more source
An Efficient Extension of Network Simplex Algorithm [PDF]
Journal of Optimization in Industrial Engineering, 2010 In this paper, an efficient extension of network simplex algorithm is presented. In static scheduling problem, where there is no change in situation, the challenge is that the large problems can be solved in a short time.
Hassan Rashidi, Edward P.K Tsang
doaj