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State-of-the-Art Review on the Treatment of Axial Spondyloarthritis. [PDF]
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Is no NSAID a good NSAID? approaches to NSAID-associated upper gastrointestinal disease
Current Gastroenterology Reports, 2004Upper gastrointestinal disease induced by use of nonsteroidal anti-inflammatory drugs (NSAIDs) remains a major problem that affects a broad segment of the population, given the frequent use of these drugs by prescription and over the counter. The emergence of the cyclooxygenase (COX)-2 selective inhibitors (coxibs) has introduced a new option that may ...
Colin W. Howden, Stephen Y. Chang
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Current Opinion in Gastroenterology, 2009
To better understand the effects of NSAIDs on the colon.An epidemiological study has confirmed that NSAIDs increase the risk of hospitalizations for lower gastrointestinal complications, though the estimated rate of hospitalization was lower than that for upper gastrointestinal complications.
Angel Lanas, Angel Ferrandez
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To better understand the effects of NSAIDs on the colon.An epidemiological study has confirmed that NSAIDs increase the risk of hospitalizations for lower gastrointestinal complications, though the estimated rate of hospitalization was lower than that for upper gastrointestinal complications.
Angel Lanas, Angel Ferrandez
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NSAIDs and cardiovascular risk
Journal of Cardiovascular Medicine, 2017NSAIDs are the most largely used class of drugs in the world, due to their large use in many diseases, in particular for the systemic inflammatory diseases. Nevertheless, today NSAIDs are less used for some of these diseases, due to several side-effects correlated to these drugs. The antiinflammatory mechanism of NSAIDs consist in the inibhition of two
Marsico F, Paolillo S, Filardi PP
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European Journal of Gastroenterology & Hepatology, 1999
There have been many studies documenting the deleterious effects of non-steroidal anti-inflammatory drugs (NSAIDs) on the gastrointestinal tract, and it is widely accepted that these agents cause mucosal damage in the stomach, duodenum, jejunum, ileum and colon.
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There have been many studies documenting the deleterious effects of non-steroidal anti-inflammatory drugs (NSAIDs) on the gastrointestinal tract, and it is widely accepted that these agents cause mucosal damage in the stomach, duodenum, jejunum, ileum and colon.
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BMJ, 2016
NSAIDs pose a clear risk to some patients and tighter regulation is justified Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs and are mainly used to alleviate pain and inflammation. NSAIDs were first introduced over a century ago and most of the commonly used NSAIDs were registered in an era with few requirements ...
Gunnar Gislason+3 more
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NSAIDs pose a clear risk to some patients and tighter regulation is justified Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs and are mainly used to alleviate pain and inflammation. NSAIDs were first introduced over a century ago and most of the commonly used NSAIDs were registered in an era with few requirements ...
Gunnar Gislason+3 more
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Hospital Practice, 1991
The ability of aspirin and related drugs to inhibit prostaglandin biosynthesis accounts for many effects of NSAIDs but does not completely explain their efficacy against inflammation. An additional mechanism may be disruption of the intracellular signal pathways responsible for activation of inflammatory cells--notably, neutrophils.
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The ability of aspirin and related drugs to inhibit prostaglandin biosynthesis accounts for many effects of NSAIDs but does not completely explain their efficacy against inflammation. An additional mechanism may be disruption of the intracellular signal pathways responsible for activation of inflammatory cells--notably, neutrophils.
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Southern Medical Journal, 1987
The use of NSAIDs masked the diagnosis of gout in nine patients with the chronic polyarticular form of the disease. The escape from detection of chronic polyarticular gout resulted in a needless dependence on NSAIDs, failure to correct the metabolic problem, and in some cases progression of joint destruction.
Scopelitis, E, McGrath, H
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The use of NSAIDs masked the diagnosis of gout in nine patients with the chronic polyarticular form of the disease. The escape from detection of chronic polyarticular gout resulted in a needless dependence on NSAIDs, failure to correct the metabolic problem, and in some cases progression of joint destruction.
Scopelitis, E, McGrath, H
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