Results 271 to 280 of about 104,757 (302)
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NSAIDs and cardiovascular disease
Heart, 2007Non-steroidal anti-inflammatory drugs (NSAIDs) are a chemically heterogeneous group of agents to treat symptoms of acute pain and chronic inflammatory and degenerative joint diseases, such as rheumatoid arthritis (RA) and osteoarthritis (OA).1 They act mostly through the inhibition of cyclooxygenase-2 (COX-2)-dependent prostanoids.
PATRIGNANI, Paola +2 more
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Cellular and Molecular Life Sciences, 2008
Regular use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with decreased incidence of cancer of the colon and other gastrointestinal organs. The chemopreventive properties of NSAIDs are due to their ability to induce apoptosis.
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Regular use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) has been associated with decreased incidence of cancer of the colon and other gastrointestinal organs. The chemopreventive properties of NSAIDs are due to their ability to induce apoptosis.
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Current Opinion in Rheumatology, 2013
Published data raise concerns about the use of nonselective NSAIDs and selective cyclo-oxygenase (COX)-2 inhibitors as anti-inflammatory or analgesic drugs in patients after a recent fracture or who are undergoing (uncemented) arthroplasty or osteotomy.
Joost J. A. de Jong +3 more
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Published data raise concerns about the use of nonselective NSAIDs and selective cyclo-oxygenase (COX)-2 inhibitors as anti-inflammatory or analgesic drugs in patients after a recent fracture or who are undergoing (uncemented) arthroplasty or osteotomy.
Joost J. A. de Jong +3 more
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NSAIDS AND THE MICROCIRCULATION OF THE STOMACH
Gastroenterology Clinics of North America, 1996In this article, the effect of NSAIDs on the gastric mucosal microcirculation was reported. Although the precise mechanism of NSAID-induced ulcerogenesis is still unknown, most NSAIDs have been shown to impair gastric mucosal microcirculation and cause gastric mucosal damage.
Nobuhiro Sato +3 more
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Orthopaedic Nursing, 1995
NSAIDs continue to be an important drug classification for management of various orthopaedic conditions. This column introduces three new drugs and updates the reader on Toradol. Adverse effects and nursing implications are addressed.
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NSAIDs continue to be an important drug classification for management of various orthopaedic conditions. This column introduces three new drugs and updates the reader on Toradol. Adverse effects and nursing implications are addressed.
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The therapeutic potential of NO‐NSAIDs
Fundamental & Clinical Pharmacology, 2003AbstractNSAIDs, including those that are selective for cyclooxygenase‐2, are among the most widely used drugs. However, these drugs produce significant side effects in the gastrointestinal and cardiorenal systems, which greatly limit their utility.
John L. Wallace, Piero Del Soldato
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AJN, American Journal Of Nursing, 1985
N onsteroidal anti-inflammatory drugs (NSAIDs) were originally introduced and marketed for the treatment of arthritis.* Now, many of these drugs are also used as general analgesics. Unlike narcotics, NSAIDs are not associated with physical dependence, addiction, or tolerance. Their analgesic action site appears to be mainly at the point of injury, that
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N onsteroidal anti-inflammatory drugs (NSAIDs) were originally introduced and marketed for the treatment of arthritis.* Now, many of these drugs are also used as general analgesics. Unlike narcotics, NSAIDs are not associated with physical dependence, addiction, or tolerance. Their analgesic action site appears to be mainly at the point of injury, that
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NSAIDs in neuroblastoma therapy
Cancer Letters, 2005Cyclooxygenases (COX) catalyse the conversion of arachidonic acid to prostaglandins. COX-2 is upregulated in several adult epithelial cancers. In neuroblastoma it has been shown that the majority of primary tumours and cell lines express high levels of COX-2, whereas normal adrenal medullas from children do not express COX-2. Treatment of neuroblastoma
Per Kogner +8 more
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Celecoxib, NSAIDs and the skeleton
Drugs of Today, 2008Treating acute and chronic musculoskeletal pain is essential for improving healing of traumatic injuries and surgical procedures, and for improving patient quality of life. Physicians are limited primarily to treating musculoskeletal pain with nonsteroidal antiinflammatory drugs (NSAIDs), cyclooxygenase type 2 (COX-2)-selective NSAIDs such as celecoxib,
Thomas W. Lysz, James Patrick O'Connor
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BMJ clinical evidence, 2016
NSAIDs are widely used. Almost 10% of people in The Netherlands used a non-aspirin NSAID in 1987, and the overall use was 11 defined daily doses per 1000 population per day. In Australia in 1994, overall use was 35 defined daily doses per 1000 population a day, with 36% of the people receiving NSAIDs for osteoarthritis, 42% for sprain and strain or low
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NSAIDs are widely used. Almost 10% of people in The Netherlands used a non-aspirin NSAID in 1987, and the overall use was 11 defined daily doses per 1000 population per day. In Australia in 1994, overall use was 35 defined daily doses per 1000 population a day, with 36% of the people receiving NSAIDs for osteoarthritis, 42% for sprain and strain or low
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