Impact of EMA regulatory label changes on systemic diclofenac initiation, discontinuation, and switching to other pain medicines in Scotland, England, Denmark, and The Netherlands [PDF]
, 2020 Purpose: In June 2013 a European Medicines Agency referral procedure concluded that diclofenac was associated with an elevated risk of acute cardiovascular events and contraindications, warnings, and changes to the product information were implemented ...
Bennie, Marion +17 more
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P003. NSAIDs for symptomatic treatment of headache [PDF]
, 2015 Background and aims Clinical observations suggest that the use of non-steroidal anti-inflammatory drugs (NSAIDs) for symptomatic treatment of headache is not in line with recommendations by international guidelines [1].
Affaitati, Giannapia +8 more
core +1 more source
Inhibition of Tendon Cell Proliferation and Matrix Glycosaminoglycan Synthesis by Non-Steroidal Anti-Inflammatory Drugs in vitro [PDF]
, 2002 The purpose of this study was to investigate the effects of some commonly used non-steroidal anti-inflammatory drugs (NSAIDs) on human tendon. Explants of human digital flexor and patella tendons were cultured in medium containing pharmacological ...
B. L HAZLEMAN +16 more
core +1 more source
British Journal of General Practice, 2016 I read with interest the editorial by Davis and Robson on the dangers of NSAIDs1 and wanted to reinforce the need for better professional and public education surrounding their risks, especially those less frequently encountered. Having recently passed my …
openaire +2 more sources
Prodrugs of NSAIDs: A Review [PDF]
The Open Medicinal Chemistry Journal, 2017 Intoroduction:Prodrug approach deals with chemical biotransformation or enzymatic conversion or involves inactive or less active bio-reversible derivatives of active drug molecules. They have to pass through enzymatic or chemical biotransformation before eliciting their pharmacological action.Methods & Materials:The two different pharmacophores ...
Pradeep Mishra +5 more
openaire +2 more sources
Back pain: from diagnosis to treatment
Медицинский совет, 2020 In today ‘s world, back pain is a heavy burden and leads to a decrease in the working capacity, quality of life of people. The choice of tactics of treatment of pain in a back is defined by the pain reason: nonspecific pain, the specific pain caused by ...
O. A. Solokha +3 more
doaj +1 more source
New sporopollenin-based β-cyclodextrin functionalized magnetic hybrid adsorbent for magnetic solid-phase extraction of nonsteroidal anti-inflammatory drugs from water samples [PDF]
Royal Society Open Science, 2018 A magnetic solid-phase extraction (MSPE) procedure on the newly synthesized magnetic β-cyclodextrin functionalized with toluene diisocyanate (TDI) as a linker and further modified with bio-polymeric spores of sporopollenin (MSp-TDI-βCD), was developed ...
Syed Fariq Fathullah Syed Yaacob +3 more
doaj +1 more source
Cypc19*17 Polymorphism as a Risk-factor for Nsaids-induced Ulcers [PDF]
, 2016 The new risk-factors for peptic ulcers induced by the use of nonsteroidal antiinflammatory drugs, such as polymorphism of different isoenzymes of cytochrome P450 were considered in the article.
Balabanseva, A. (Alexandra) +2 more
core +2 more sources
NSAIDs as a Drug Repurposing Strategy for Biofilm Control
Antibiotics, 2020 Persistent infections, usually associated with biofilm-producing bacteria, are challenging for both medical and scientific communities. The potential interest in drug repurposing for biofilm control is growing due to both disinvestment in antibiotic R&D ...
C. Leão, A. Borges, M. Simões
semanticscholar +1 more source
Use of gastroprotective agents in recommended doses in hospitalized patients receiving NSAIDs: a drug utilization study [PDF]
, 2006 OBJECTIVE: In recent years, studies investigated to what extend recommendations for co-prescribing gastroprotective agents in prevention of NSAID-induced gastrointestinal complications are followed in clinical practice.
Bilušić, Marinko +6 more
core +1 more source