Results 31 to 40 of about 176,388 (298)

Dysmenorrhea: Epidemiology, Causes and Current State of the Art for Treatment

Clinical and Experimental Obstetrics & Gynecology, 2023
Objectives: This narrative review analyzes current knowledge on the pathophysiology of dysmenorrhea and the different therapeutic options currently available for adolescents and young women.
Roberta Francavilla, Maddalena Petraroli, Giulia Messina, Brigida Stanyevic, Arianna Maria Bellani, Susanna MR Esposito, Maria E. Street   +6 more
doaj   +1 more source

EAACI/ENDA Position Paper: Diagnosis and management of hypersensitivity reactions to non‐steroidal anti‐inflammatory drugs (NSAIDs) in children and adolescents

Pediatric Allergy and Immunology, 2018
Non‐steroidal anti‐inflammatory drugs (NSAIDs) are commonly used in the pediatric population as antipyretics/analgesics and anti‐inflammatory medications.
M. Kidon, N. Blanca‐Lopez, E. Gomes, I. Terreehorst, L. Tanno, C. Ponvert, Chiang Wen Chin, J. Caubet, O. Soyer, F. Mori, M. Blanca, M. Atanasković-Marković   +11 more
semanticscholar   +1 more source

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer's disease in rodent models

Nature Communications, 2016
Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit cyclooxygenase-1 (COX-1) and COX-2 enzymes. The NLRP3 inflammasome is a multi-protein complex responsible for the processing of the proinflammatory cytokine interleukin-1β and is implicated in many ...
Michael J. D. Daniels, J. Rivers-Auty, T. Schilling, Nicholas G. Spencer, William Watremez, Victoria Fasolino, S. J. Booth, Claire S. White, A. Baldwin, S. Freeman, Raymond Wong, Clare H Latta, Shi Yu, Joshua Jackson, N. Fischer, V. Koziel, T. Pillot, J. Bagnall, S. Allan, P. Paszek, J. Galea, M. Harte, C. Eder, C. Lawrence, D. Brough   +24 more
semanticscholar   +1 more source

Physician Referral Patterns to Physical Therapists for Managing Knee Osteoarthritis: A Retrospective Analysis of Electronic Health Records From an Integrated Health System

Arthritis Care &Research, EarlyView.
Objective This study aims to describe the frequency and timing of physician referrals to physical therapists (PTs) and other treatments prescribed over 12 months in patients with recent onset of knee osteoarthritis (KOA). The study also aims to identify determinants of early PT referrals.
Samannaaz S. Khoja, Joel M. Stevans, Gustavo J. Almeida, Clair Smith, Janet K. Freburger   +4 more
wiley   +1 more source

Anti-inflammatory and antioxidant activities of ethylacetate fraction of Sida linifolia L. (Malvaceae)

International Journal of Plant Based Pharmaceuticals, 2023
Sida linifolia L., a known weed found in West Africa and other parts of the world, is being used in African traditional medicine for many purposes, including the relief of uncomfortable teething, and the prevention of malaria.
Nicodemus Emeka Nwankwo, Emmanuel Chigozie Aham, Emmanuel Henry Ezenabor, Diana-Mary Ginika Chidozie   +3 more
doaj   +1 more source

Cost‐Effectiveness of Low‐Dose Colchicine Prophylaxis When Starting Allopurinol Using the “Start‐Low Go‐Slow” Approach for Gout: Evidence From a Noninferiority Randomized Double‐Blind Placebo‐Controlled Trial

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko, Ross Wilson, Nicola Dalbeth, J. Haxby Abbott, Lisa Stamp   +4 more
wiley   +1 more source

Temporal Trends in and Associations With Nonsteroidal Anti‐inflammatory Drug Prescription in Adult and Pediatric Patients With Inflammatory Bowel Disease

Arthritis Care &Research, EarlyView.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against nonsteroidal anti‐inflammatory drug (NSAID) use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal
Adam S. Mayer, Rui Xiao, Andrew Grossman, Meenakshi Bewtra, Michael D. George, Pamela F. Weiss   +5 more
wiley   +1 more source

Nonsteroidal anti-inflammatory drug administration to periparturient cows to reduce postpartum pain-related behaviours

Veterinary Evidence
Question In periparturient cows does the administration of nonsteroidal anti-inflammatory drugs (NSAIDs) aid in reducing pain-related behaviours after parturition when compared to cows not administered NSAIDs?
Amelia Cannadine
doaj   +1 more source

Personalization of the use of non-steroidal anti-inflammatory drugs for musculoskeletal diseases. Resolution on the results of the Meeting of Experts of December 13, 2017

Медицинский совет, 2018
The personalization of therapy is one of the innovative approaches gaining an increasingly strong foothold in modern medicine, implying an individual approach to each patient, taking into account the individual characteristics of the patient and the ...
A. E. Karateev, A. M. Lila, I. S. Dydykina, P. R. Kamchatnov, S. O. Mazurenko, M. V. Naprienko, D. S. Novikova, O. P. Ostroverkhov, M. V. Pchelintsev   +8 more
doaj   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source