Serum histamine in non-small cell lung cancer: An observational study in the context of allergo-oncology. [PDF]
Rongrong Z +4 more
europepmc +1 more source
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang +4 more
wiley +1 more source
A Tale of Two Periods: The Evolution of Determinants and CVD Mortality Risk in Metastatic NSCLC. [PDF]
Xia J, Pang Y, Yang Y, Teng J, Lin Q.
europepmc +1 more source
This study reveals that high TMB in lung adenocarcinoma correlates with better survival prognosis and lower immune/stromal scores. Through WGCNA and consensus clustering, we identify two LUAD subtypes with distinct prognoses and mutation frequencies, offering novel insights for immunotherapy response prediction and prognosis stratification.
Haiyong Wu +7 more
wiley +1 more source
Investigating the Mechanism of Jiawei Weijin Decoction in Treating Non-Small Cell Lung Cancer Using Network Pharmacology, Bioinformatics Analysis and Experimental Validation. [PDF]
Xu B +8 more
europepmc +1 more source
Abstract Patients with recurrent high‐grade glioma (rHGG) have a poor prognosis with median progression‐free survival (PFS) of <7 months. Responses to treatment are heterogenous, suggesting a clinical need for prognostic models. Bayesian data analysis can exploit individual patient follow‐up imaging studies to adaptively predict the risk of progression.
Daniel J. Glazar +5 more
wiley +1 more source
Single-cell RNA-seq reveals gene expression heterogeneity in NSCLC and its link to the immune microenvironment. [PDF]
Ren J, Zhang H, Wu H.
europepmc +1 more source
Mechanistic Learning for Predicting Survival Outcomes in Head and Neck Squamous Cell Carcinoma
ABSTRACT We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK) modeling with various machine learning (ML) models to address the challenge of predicting post‐progression survival (PPS)—the duration from the time of documented disease progression to death—and overall survival (OS) in Head and Neck Squamous Cell ...
Kevin Atsou +4 more
wiley +1 more source
Successful treatment of osimertinib-resistant EGFR-mutant NSCLC with acquired BRAF V600E mutation using triple combination therapy: a case report with pathological confirmation. [PDF]
Lin M, Chen X, Lin F, Yang Y.
europepmc +1 more source

