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Diagnostic and prognostic roles of circulating EVs circ_PPAPDC1A in ICIs resistance in NSCLC. [PDF]
Zou FW +6 more
europepmc +1 more source
Clinical study of aumolertinib versus osimertinib in the treatment of EGFR-mutated advanced non-small cell lung cancer. [PDF]
Yang SX +6 more
europepmc +1 more source
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Osimertinib with or without Chemotherapy in EGFR-Mutated Advanced NSCLC.
New England Journal of Medicine, 2023BACKGROUND Osimertinib is a third-generation epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) that is selective for EGFR-TKI-sensitizing and EGFR T790M resistance mutations.
D. Planchard +20 more
semanticscholar +1 more source
Overall Survival with Osimertinib in Resected EGFR-Mutated NSCLC.
New England Journal of Medicine, 2023BACKGROUND Among patients with resected, epidermal growth factor receptor (EGFR)-mutated, stage IB to IIIA non-small-cell lung cancer (NSCLC), adjuvant osimertinib therapy, with or without previous adjuvant chemotherapy, resulted in significantly longer ...
M. Tsuboi +19 more
semanticscholar +1 more source
Amivantamab plus Chemotherapy in NSCLC with EGFR Exon 20 Insertions.
New England Journal of Medicine, 2023BACKGROUND Amivantamab has been approved for the treatment of patients with advanced non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 20 insertions who have had disease progression during or after platinum-based ...
Caicun Zhou +27 more
semanticscholar +1 more source
Onkologische Welt, 2023
Nach Daten der Studie FLAURA2 zeigt Osimertinib plus Chemotherapie in der Behandlung des nicht-kleinzelligen Lungenkarzinoms (NSCLC) einen statistisch signifikanten Vorteil beim progressionsfreien Überleben (PFS) im Vergleich zu Osimertinib allein ...
semanticscholar +1 more source
Nach Daten der Studie FLAURA2 zeigt Osimertinib plus Chemotherapie in der Behandlung des nicht-kleinzelligen Lungenkarzinoms (NSCLC) einen statistisch signifikanten Vorteil beim progressionsfreien Überleben (PFS) im Vergleich zu Osimertinib allein ...
semanticscholar +1 more source
Applications of genomics in NSCLC
Lung Cancer, 2005Cisplatin-based chemotherapy has long been the cornerstone of non-small cell lung cancer (NSCLC) management. However, median survival rarely exceeds 1 year. The identification of molecular markers can help to predict response, leading to a broad implementation of the new concept of customized chemotherapy.
ROSELL R +9 more
openaire +5 more sources
A review of Osimertinib in NSCLC and pharmacist role in NSCLC patient care
Journal of Oncology Pharmacy Practice, 2020Lung cancer is a complex, genetically heterogeneous disease. It is the most common cause of cancer-related deaths worldwide. Non-small cell lung cancer (NSCLC) represents the majority of the diagnosed lung cancer cases. Osimertinib is a new treatment option that demonstrated a superior efficacy over standard epidermal growth factor receptor tyrosine ...
Osama M Al-Quteimat, Amer M Amer
openaire +3 more sources
Journal of Clinical Oncology, 2014
e18516 Background: Lung cancer has a poor prognosis, with 15-20% five-years survival rate. However, lung cancer treatment has in the last years taken advantage of newly developed targeted therapies...
Eivind Hovig +9 more
openaire +2 more sources
e18516 Background: Lung cancer has a poor prognosis, with 15-20% five-years survival rate. However, lung cancer treatment has in the last years taken advantage of newly developed targeted therapies...
Eivind Hovig +9 more
openaire +2 more sources
Lung Cancer, 2004
The prognosis of bronchogenic carcinoma in stage III N2 is poor. Five-year survival ranges between 0 and 5%. Lymph-node involvement itself still is the main prognostic factor. Complete lymphadenectomy improves long-term survival in contrast to lymph-node sampling.
Thomas Kyriss +4 more
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The prognosis of bronchogenic carcinoma in stage III N2 is poor. Five-year survival ranges between 0 and 5%. Lymph-node involvement itself still is the main prognostic factor. Complete lymphadenectomy improves long-term survival in contrast to lymph-node sampling.
Thomas Kyriss +4 more
openaire +2 more sources

