Results 171 to 180 of about 3,482,856 (317)

Nuclear PD-L1: an emerging oncogenic driver and promising therapeutic target in cancer. [PDF]

J Biomed Sci
Guo C, Fan Z, Guo C, Yang Y, Hou H, Sun D.   +5 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Nuclear energy in the 21st century the World Nuclear University primer = World Nuclear University primer [PDF]

, 2006
World Nuclear Association, Hore-Lacy, Ian, World Nuclear University   +2 more
core  

The nuclear basket nucleoporin MLP1 is required to maintain nuclear integrity, and mitotic fidelity in Trypanosoma brucei. [PDF]

PLoS Negl Trop Dis
Yagoubat A, Crobu L, Stanojcic S, Kuk N, Sarrazin A, Blanchard MP, Bastien P, Lévêque MF, Berry L, Sterkers Y.   +9 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Social and Ethical Considerations of Nuclear Power Development [PDF]

A new urgency is emerging around nuclear power development and this urgency is accentuated by the post-tsunami events at the Fukushima Daiichi nuclear power plant in Japan.
Parkins, John R., Haluza-DeLay, Randolph
core   +1 more source

Correction: Biochemical failure after radical prostatectomy with PSA ≤ 1 ng/mL: prediction of PSMA-positive metastatic disease. [PDF]

Ann Nucl Med
Santo G, Rosarno H, Restuccia A, Cascini GL, Grillone F, Cicone F.   +5 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The Lamin Proteins in Nuclear Structure, Functions, and Laminopathies. [PDF]

Cells
Zhao G, Chen Z, Yang C, Liu M, Wang W, Zhang C.   +5 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source