Results 21 to 30 of about 881,714 (230)
GEN-IV LFR development: Status & perspectives [PDF]
, 2018 Since Lead-cooled Fast Reactors (LFR) have been conceptualized in the frame of Generation IV International Forum (GIF), great interest has focused on the development and testing of new technologies related to Heavy Liquid Metal (HLM) nuclear reactors. In
Bassini, Serena +6 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Inclusion of chemical effect in a fully coupled THM finite element code [PDF]
, 2018 Bentonite-rich clays can be used as a buffer / backfill material in deep geological repositories for nuclear waste. The prediction of the long-term performance of a buffer / backfill in such a complex environment, where the temperature, humidity and ...
Abed, A. A. +3 more
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Simulation of chemical reaction dynamics on an NMR quantum computer
, 2011 Quantum simulation can beat current classical computers with minimally a few tens of qubits and will likely become the first practical use of a quantum computer.
C. Zalka +12 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Hadron Chemistry at High-PT with Identified Particles
, 2009 We discuss mechanisms that change the hadron chemistry for high momentum particles emitted in high energy nuclear collisions. We argue that particle ratios naturally tend to be different from jets in the vacuum. We show results of computations in a model
Marvin L. Marshak, Rainer J. Fries
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source