Results 61 to 70 of about 3,958,335 (294)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Nitrido Technetium-99 m Core in Radiopharmaceutical Applications: Four Decades of Research
Inorganics, 2019 The knowledge on element 43 (Tc) of the periodic table, built over the years through the contributions given by the close relationship between chemistry and nuclear medicine, allowed the development of new and increasingly effective radiopharmaceuticals ...
Cristina Bolzati, Alessandro Dolmella
doaj +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Department of Chemistry Newsletter (Fall/Winter 1991)
, 1991 The newsletter of the Department of Chemistry, published once or twice a year, highlights people, events, and facilities. Content includes brief articles on new faculty hires, faculty and staff retirements, obituaries, major facilities and equipment ...
Department of Chemistry
core +1 more source
Measurements of stable ruthenium fission products in nuclear reactor fuel samples
Scientific ReportsRuthenium isotopes produced by fission in nuclear materials could be valuable signatures for nuclear verification or non-proliferation monitoring. In this study, ruthenium (Ru), uranium (U), and plutonium (Pu) isotope ratios and concentrations were ...
Genna M. Patton +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Applications of NMR in nuclear chemistry
The adaptation, worldwide, of a number of NMR spectrometers has increased nuclear chemistry capability in high-resolution liquid NMR. In the solid-state, the advent of ‘nuclearised’ MASNMR allows the deployment of high-resolution solid-state methods ...
Berthon, Claude +2 more
core +1 more source
The Offshore Floating Nuclear Plant Concept
, 2016 A new offshore floating nuclear plant (OFNP) concept with high potential for attractive economics and an unprecedented level of safety is presented. OFNP creatively combines state-of-the-art light water reactors and floating platforms similar to those ...
Buongiorno, Jacopo +3 more
core +1 more source
Dynamic Combinatorial Libraries: From Exploring Molecular Recognition to Systems Chemistry [PDF]
, 2013 Dynamic combinatorial chemistry (DCC) is a subset of combinatorial chemistry where the library members interconvert continuously by exchanging building blocks with each other.
Otto, Sijbren, +9 more
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Pharmaceutics, 2019 To date, our understanding of the Substance P (SP) and neurokinin 1 receptor (NK1R) system shows intricate relations between human physiology and disease occurrence or progression.
Agnieszka Majkowska-Pilip +2 more
doaj +1 more source