Results 211 to 220 of about 4,065 (278)
Abstract The Iranian revolution of 1979 is generally portrayed either as the catalyst of sectarian polarization in the Middle East or, more recently, as the foundation of a pragmatic grand strategy shaped by geopolitical insecurity and learning forged by decades of war. This article challenges this binary opposition between ideology and strategy.
Alabbas F. Alsudani
wiley +1 more source
BAHD acyltransferases drive metabolic diversification in plants by coupling conserved catalytic scaffolds with regulatory flexibility, enabling stress adaptation and ecological specialisation. ABSTRACT BAHD acyltransferases constitute one of the most versatile enzyme superfamilies in plants, catalysing the acylation of alcohols, amines, polyamines, and
Muhammad Mubashar Zafar +7 more
wiley +1 more source
ABSTRACT From all the knowledge that would emerge as relevant to it over infinite time, a risk analysis must be based on the cross‐section available at its undertaking. This creates a knowledge gap, which can lead to surprises. To address a similar problem in economic decision‐making, G. L. S. Shackle developed potential surprise theory (PST).
James Derbyshire
wiley +1 more source
The E3 Ligase RNF8 Promotes Ubiquitination and Degradation of ChREBPα During Liver Stress Response
During MASH development, increasing hepatic stress signals, particularly a combination of lipotoxicity (palmitate) and inflammation (TNFα), trigger JNK, the key stress‐activated protein kinase. Activated JNK recruits RNF8, a stress‐induced E3 ligase, to promote ubiquitination and proteasomal degradation of the ChREBPα protein.
Yuee Zhao +8 more
wiley +1 more source
Integrative Approaches to Treating Cellular Senescence in Kidney Disease. [PDF]
Misawa T, A A, Hickson LJ, Wolfram J.
europepmc +1 more source
Nuclear Deterrence and Compellence
This chapter examines whether nuclear superiority matters for compellent threats. Drawing on the Militarized Compellent Threat (MCT) data set, the same data set used by nuclear irrelevance theorists, it finds that the nuclear balance of power is central to patterns of international coercion.
Matthew Kroenig
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Science, 2022
In October 1962, the United States and the Soviet Union squared off in what game theorist and Nobel laureate Thomas Schelling described as a nuclear game of “chicken” that threatened humanity’s survival. The Cuban Missile Crisis spurred six decades of efforts to limit the spread of nuclear weapons and inspired a generation of scientists to think ...
openaire +2 more sources
In October 1962, the United States and the Soviet Union squared off in what game theorist and Nobel laureate Thomas Schelling described as a nuclear game of “chicken” that threatened humanity’s survival. The Cuban Missile Crisis spurred six decades of efforts to limit the spread of nuclear weapons and inspired a generation of scientists to think ...
openaire +2 more sources
The Critique of Nuclear Deterrence
The Adelphi Papers, 1983The purpose of this Paper is to enumerate some of the main grounds for concern about nuclear deterrence and also to try to suggest where the critique of nuclear deterrence leads.
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