Results 41 to 50 of about 7,608,807 (307)

Manufacturing Risk Identification in the Steel Industry [PDF]

open access: yesE3S Web of Conferences, 2020
The steel manufacturing industry is an inseparable part of the nuclear power plant construction project. This industry is a business full of dynamics, risks, and challenges.
Dewi Dharu   +4 more
doaj   +1 more source

SYMMETRY ENERGY IN NUCLEAR SURFACE [PDF]

open access: yesInternational Journal of Modern Physics E, 2009
Interplay between the dependence of symmetry energy on density and the variation of nucleonic densities across nuclear surface is discussed. That interplay gives rise to the mass dependence of the symmetry coefficient in an energy formula. Charge symmetry of the nuclear interactions allows to introduce isoscalar and isovector densities that are ...
Lee, Jenny, Danielewicz, Paweł
openaire   +4 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Design, Experiment, and Commissioning of the Spent Fuel Conveying and Loading System of HTR-PM

open access: yesScience and Technology of Nuclear Installations, 2022
The Chinese high-temperature gas-cooled reactor pebble-bed module, HTR-PM, began fuel loading in August 2021. The reactor refuels continuously, while the spent fuel is discharged from the core.
Bin Wu   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

A PROPOSAL OF PROCESS VALIDATION IN THE IMPLEMENTATION OF GOOD MANUFACTURING PRACTICES IN BRACHYTHERAPY SOURCES PRODUCTION

open access: yesBrazilian Journal of Radiation Sciences, 2021
New laboratories for brachytherapy sources production are being implemented in our facility at IPEN, in São Paulo. A great challenge implementing a production laboratory is to comply with the Good Manufacturing Practices (GMPs), which involves process ...
Tatyana Spinosa Baptista   +5 more
doaj   +1 more source

Summary Report of the INL-JISEA Workshop on Nuclear Hybrid Energy Systems [PDF]

open access: yes, 2012
The Institute for Nuclear Energy Science and Technology (INEST) and the Joint Institute for Strategic Energy Analysis (JISEA) co-sponsored an international workshop to identify research topics important in advancing the potential use of hybrid systems ...
Cherry, R.   +5 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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