Results 81 to 90 of about 693,542 (303)

The GEANT4 Object Oriented Simulation Tookit [PDF]

open access: yes, 1999
Geant4 is a toolkit for the simulation of the passage of particles through matter, developed with advanced software engineering techniques. Its application areas include high energy and nuclear physics experiments, space physics, $9 medical physics and ...
Pia, M G
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

The rechargeable battery using uranium as an active material

open access: yesScientific Reports
We first demonstrate a nonaqueous rechargeable battery using uranium and iron as active materials. This uranium-iron battery achieves an open-circuit voltage of approximately 1.3 V, exhibits stable cycling performance, and delivers a good Coulombic ...
Kazuki Ouchi   +2 more
doaj   +1 more source

Korea's nuclear past, present, and future [PDF]

open access: yes, 2008
노트 : As the chairman of KEPIC, the Korea Electric Power Industry Code Committee, for the past 15 years, C.K. Lee has mobilized and managed 350 engineering professors and professional engineers dispatched from six engineering-related academic societies ...
Lee, Chang Kun
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Ядерна енергетика і наслідки Чорнобильської катастрофи [PDF]

open access: yes, 2009
Автори статті переконливо доводять пріоритетність ядерної енергетики над усіма іншими способами отримання енергії для існування і розвитку нашої техногенної цивілізації.
Araújo,Valdevane Rocha   +6 more
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Significant role of secondary electrons in the formation of a multi-body chemical species spur produced by water radiolysis

open access: yesScientific Reports
Scientific insights into water photolysis and radiolysis are essential for estimating the direct and indirect effects of deoxyribonucleic acid (DNA) damage. Secondary electrons from radiolysis intricately associated with both effects.
Takeshi Kai   +6 more
doaj   +1 more source

Development of failure evaluation method for BWR Lower head in severe accident; high temperature creep test and creep damage model

open access: yesMechanical Engineering Journal, 2017
After the Fukushima Daiichi nuclear power plant accident due to the pacific coast of Tohoku earthquake and Tsunami, we have been developing an analysis method considering creep damage mechanisms based on three-dimensional analysis in order to estimate ...
Yoshihito YAMAGUCHI   +5 more
doaj   +1 more source

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