Results 221 to 230 of about 7,084,452 (309)

Introduction to nuclear engineering [PDF]

Journal of Chemical Education, 1959
openaire   +1 more source

Synergistic Tuning of Boron-Containing Concrete for Neutron Shielding: Mix Design, Dosage Optimization, and Mechanistic Insights. [PDF]

Materials (Basel)
Xu C, Zhang Z, Kong X, Li Y, Xu S, Yang Z, Tian Y.   +6 more
europepmc   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Correction: Myeloid-derived growth factor suppresses VSMC dedifferentiation and attenuates postinjury neointimal formation in rats by activating S1PR2 and its downstream signaling. [PDF]

Acta Pharmacol Sin
Yang S, Li HW, Tian JY, Wang ZK, Chen Y, Zhan TT, Ma CY, Feng M, Cao SF, Zhao Y, Li X, Ren J, Liu Q, Jin LY, Wang ZQ, Jiang WY, Zhao YX, Zhang Y, Liu X.   +18 more
europepmc   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Targeted Nanoparticle Delivery CRISPR/Cas9: overcoming biological barriers, enhancing stability, and improving therapeutic precision. [PDF]

Int J Pharm X
Sriwidodo S, Suhandi C, Sagitasa S, Davinali BAA, Maksum IP, Safuan S.   +5 more
europepmc   +1 more source

Nationwide Survey of Association Between Fever and Epileptic Seizure in CDKL5 Deficiency Disorder Revealed Therapeutic Implications

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective CDKL5 deficiency disorder (CDD) is a rare, severe developmental and epileptic encephalopathy. There is a pressing need to develop effective and sustainable therapeutic strategies. We aimed to investigate the causal association between febrile episodes and epileptic seizures for therapeutic implications in CDD patients.
Siyi Wang, Jialin Du, Jinghui Liu, Dongmei Hu, Hongxin Wang, Xiaoxiao Man, Lehong Gao, Shimin Hu, Xianghong Meng, Hongyang Zhao, Minjing Hu, Yingxue Yang, Zhiqi Xiong, Liankun Ren   +13 more
wiley   +1 more source

Nuclear export as a therapeutic vulnerability in ZFTA-RELA ependymoma. [PDF]

Neuro Oncol
Ippagunta SM, Arabzade A, Varadharajan S, Emanus E, Bland A, Kardian A, Laboe N, Sun H, Zheng T, Hancock A, Zhai M, Caesar E, Park M, Orisme W, Johnson M, Rodgers B, Turner GH, Steinberg J, Freeman B, Roussel MF, Shelat A, Kriwacki RW, Merchant TE, Deneen B, Taylor MD, Agnihotri S, Pruett-Miller S, Steele JA, Kavirayani AM, Ellison DW, Onar-Thomas A, Robinson GW, Mack SC, Bertrand KC.   +33 more
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Hierarchy-Aware AI Nuclear Phenotyping in Human iPSC-Derived Cardiomyocytes: A Preclinical Framework for Imaging Biomarker Development. [PDF]

Life (Basel)
Sufian MA, Qazi N, Ruchaya P, Berardinelli N, Ghazanfar MA, Baral D.   +5 more
europepmc   +1 more source