Results 101 to 110 of about 2,696,237 (374)
Cell line derived xenograft mouse models are a suitable in vivo model for studying tumor budding in colorectal cancer [PDF]
, 2019 Tumor budding (TB) is an important prognostic parameter in colorectal cancer (CRC) and associated with metastasis. However, the mechanisms of TB have not been fully elucidated and a major limitation is the absence of in vivo models.
Dawson, Heather +6 more
core +2 more sources
Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller +6 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Journal of Natural Resources and Development, 2012 Different Energy options have been the driving force for the world economy with an evolution in types and sources. Decades ago choosing what energy option to use did not call for much debate as issues of sustainability, pressure on our environment, and ...
Eric Ndeh Mboumien Ngang
doaj +1 more source
Systems Patholopgy of Social Organizations: Fukushima Nuclear Catastrophe 3.11 [PDF]
, 2011 The magnitude 9.0 earthquake and tsunami that struck northeast Japan on March 11, 2011, were unavoidable natural disasters, but we consider the subsequent breakdown of the Fukushima nuclear power plants to be a catastrophe created by avoidable human ...
Atsuji Shigeo +9 more
core +1 more source
Fabricated humans? Human genetics, ethics and the Christian wisdom tradition [PDF]
, 2005 This is a PDF version of an article published in Dialog© 2005. The definitive version is available at www.blackwell-synergy.com.This article discusses moral and ethical issues surrounding genetic screening and testing and argues that principles of ...
Deane-Drummond, Celia
core +2 more sources
Neuroinflammation in GAD65 Antibody‐Associated Epilepsy Measured Using [18F]DPA‐714 PET/MRI
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The timing for initiating immunotherapy in patients with glutamic acid decarboxylase 65 (GAD65) antibody‐associated epilepsy is a challenge. We used the translocator protein radioligand [18F]DPA‐714 and PET to evaluate brain microglial activation.
Jingjing Chen +10 more
wiley +1 more source
Protocol for isolating nuclei from frozen fish heart tissue for single-cell genomic assays
STAR ProtocolsSummary: Unbiased isolation of intact single nuclei from complex tissues, such as cryopreserved hearts, for massively parallel single-cell genomic assays is particularly challenging.
Chaoguang Wei +5 more
doaj +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
The Imperative for Nuclear Responsibility: Facing the Weapons Legacy in School [PDF]
, 1993 Nuclear industry\u27s pro-uranium mining campaign in Saskatchewan public ...
Regnier, Robert
core +1 more source