Results 141 to 150 of about 426,270 (312)

E-LENS: User Requirements-Oriented AI Ethics Assurance [PDF]

arXiv
Despite the much proliferation of AI ethical principles in recent years, there is a challenge of assuring AI ethics with current AI ethics frameworks in real-world applications. While system safety has emerged as a distinct discipline for a long time, originated from safety concerns in early aircraft manufacturing.
arxiv  

3D In Vitro Glioma‐Neuron‐Astrocyte Biomimetic Composites Recapitulate Key Molecular Mechanisms Linked to Glioblastoma Multiforme Pathophysiology

Advanced Functional Materials, EarlyView.
Glioblastoma multiforme is the most devastating and incurable brain tumor. To better study this disease, a 3D model is developed using a hyaluronic acid‐based hydrogel combined with a multicellular approach. This model recapitulates in vivo brain stiffness, cell‐extracellular matrix and cell‐cell interactions and the tumor's hijacking function with the
Mateo S. Andrade Mier, Esra Türker, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Panthipa Suwannakot, Benedikt Gantert, Abhinav Singh, Vanessa Moessler, Annemarie Sodmann, Nicoletta Murenu, Joachim Schenk, Natascha Schaefer, Torsten Blunk, Aldo R. Boccaccini, Tessa C. Lühmann, Jörg Tessmar, Jeremy M. Crook, Eva Tomaskovic‐Crook, Paul D. Dalton, Gregor Lang, Robert Blum, Reiner Strick, Silvia Budday, Katrin G. Heinze, Carmen Villmann   +26 more
wiley   +1 more source

Tesla's Autopilot: Ethics and Tragedy [PDF]

arXiv
This case study delves into the ethical ramifications of an incident involving Tesla's Autopilot, emphasizing Tesla Motors' moral responsibility. Using a seven-step ethical decision-making process, it examines user behavior, system constraints, and regulatory implications.
arxiv  

High‐Fidelity Directed Self‐Assembly Using Higher‐χ Polystyrene‐Block‐Poly(Methyl Methacrylate) Derivatives for Dislocation‐Free Sub‐10 nm Features

Advanced Functional Materials, EarlyView.
The relationship between primary polymer structure and pattern quality in the directed self‐assembly of chemically modified polystyrene‐block‐poly(methyl methacrylate) derivatives is explored. The perpendicular lamellae are aligned, with a periodicity below 20 nm. No parallel orientations or dislocations form, and line patterns are well defined over an
Shinsuke Maekawa, Lander Verstraete, Hyo Seon Suh, Takehiro Seshimo, Takahiro Dazai, Kazufumi Sato, Kan Hatakeyama‐Sato, Yuta Nabae, Teruaki Hayakawa   +8 more
wiley   +1 more source

Protocol for the purification and analysis of nuclear UFMylated proteins

STAR Protocols
Summary: Protein UFMylation regulates numerous cellular processes including ribosome quality control and nuclear DNA repair. Here, we present a technique to isolate nuclei and purify UFMylated proteins under denaturing non-reducing conditions from ...
Pudchalaluck Panichnantakul, Marlene Oeffinger   +1 more
doaj  

Engineering the Metal/Oxide Interfacial O‐Filling Effect to Tailor Oxygen Spillover for Efficient Acidic Water Oxidation

Advanced Functional Materials, EarlyView.
The oxygen spillover from Ir to the oxide support with interfacial oxygen vacancies during OER is revealed. These interfacial oxygen vacancies as an oxygen transport zone not only regulate the in situ Ir catalytic structure toward boosted activity but also suppress Ir over‐oxidation via directional OH‐filling effects, thereby ensuring overall high ...
Yu Zhu, Fei Guo, Qiliang Wei, Feiyan Lai, Runzhe Chen, Jianing Guo, Manxi Gong, Shunqiang Zhang, Zichen Wang, Jun Zhong, Guanjie He, Niancai Cheng   +11 more
wiley   +1 more source

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

Advanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen, Pengfei Zhang, Fathima Shana Pattar Kadavan, Zhaoning Xu, Tien Thanh Nguyen, Wenshao Li, Manh Tuong Nguyen, Chung Kim Nguyen, Duy Quang Pham, Thi Giang Tuyet Pham, Andrew Hayles, Markos Negash Alemie, Jitraporn Vongsvivut, Vincent Chan, Stephen Peter Kidd, Yunpeng Zhao, Krasimir Vasilev, Vi Khanh Truong   +17 more
wiley   +1 more source

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Using Recycled Materials in a Novel Dual Binder System for Hard Carbon Anodes: Closing the Loop Toward Sustainable Li‐/Na‐ion Batteries

Advanced Functional Materials, EarlyView.
The study explores for the first time the use of polyvinyl butyral (PVB), particularly recycled PVB, as a sustainable binder for Li/Na‐based electrodes in the framework of the H2020 SUNRISE EU project. Findings revealed that electrodes bound with a sustainable PAA/PVB mixture demonstrated exceptional rate capability and high initial Coulombic ...
Hamideh Darjazi, Alessandro Piovano, Giuseppina Meligrana, Giuseppe A. Elia, Claudio Gerbaldi   +4 more
wiley   +1 more source

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source