Results 241 to 250 of about 426,270 (312)

AKT1 Phosphorylates FDX1 to Promote Cuproptosis Resistance in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study demonstrates that copper activates the AKT signaling pathway, which inhibits ferredoxin‐1 (FDX1), a key regulator of cuproptosis. AKT1‐mediated FDX1 phosphorylation not only abrogates FDX1‐induced cuproptosis and aerobic respiration but also promotes glycolysis.
Zicheng Sun   +10 more
wiley   +1 more source

Retraction notice to "The significance of essential oils and their antifungal properties in the food industry: A systematic review" [Heliyon 9 (2023) e21386]. [PDF]

open access: yesHeliyon
Abdi-Moghadam Z   +13 more
europepmc   +1 more source

Novel Solution‐Processed Fe2O3/WS2 Hybrid Nanocomposite Dynamic Memristor for Advanced Power Efficiency in Neuromorphic Computing

open access: yesAdvanced Science, EarlyView.
Solution‐processed approach for integration of Fe2O3/WS2 nano‐hybrid composite memristor devices. Remarkable switching characteristics and excellent durability for up to 105 cycles. The device shows ultra‐low energy consumption of 0.072 pJ and excellent environmental stability.
Faisal Ghafoor   +11 more
wiley   +1 more source

Acute macular neuroretinopathy occurrence in a Behçet disease patient: a case report. [PDF]

open access: yesJ Ophthalmic Inflamm Infect
Mabchour A   +4 more
europepmc   +1 more source

FGF2 Mediated USP42‐PPARγ Axis Activation Ameliorates Liver Oxidative Damage and Promotes Regeneration

open access: yesAdvanced Science, EarlyView.
USP42 is identified as a novel DUB of PPARγ in hepatocytes. USP42 mediated PPARγ deubiquitylation determines its transcriptional preference on proliferative and redox balance genes. USP42 knockdown exacerbates liver damage and delays regeneration. FGF2 is the upstream signal that initiates and activates the USP42‐PPARγ axis.
Nanfei Yang   +16 more
wiley   +1 more source

Pinoresinol Diglucoside Attenuates Nuclear Receptor Coactivator 4‐Mediated Ferritinophagy Associated with Cisplatin‐Induced Hearing Loss

open access: yesAdvanced Science, EarlyView.
Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen   +12 more
wiley   +1 more source

Transcriptomic Profiling Unveils EDN3+ Meningeal Fibroblasts as Key Players in Sturge‐Weber Syndrome Pathogenesis

open access: yesAdvanced Science, EarlyView.
Sturge‐Weber syndrome (SWS) is characterized by leptomeningeal vascular malformations, leading to seizures and stroke. Analysis of 119 446 brain cells from SWS patients uncovered distinct cell heterogeneity and identified an EDN3⁺ meningeal fibroblast cluster, with WNT5A emerging as a potential key driver of SWS progression and a promising therapeutic ...
Daosheng Ai   +14 more
wiley   +1 more source

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