Results 251 to 260 of about 663,366 (347)

Skin‐Like Tri‐Modal Sensors Based on Soft Piezoelectric and Ionic Composites

open access: yesAdvanced Materials Technologies, EarlyView.
Inspired by the multimodal perception of human skin, a soft, skin‐like tri‐modal sensor is presented. The device incorporates an ionically conductive, piezoelectric, elastic composite as its active layer, enabling independent detection of temperature, static strain, and dynamic strain within a single two‐terminal architecture.
Liren Wang   +9 more
wiley   +1 more source

Ultra‐Flexible Dual‐Band Organic Photodetectors for Visible and Near‐Infrared Sensing

open access: yesAdvanced Optical Materials, EarlyView.
An ultra‐flexible dual‐band organic photodetector with a total thickness of 5.6 µm for bio‐sensing is developed. It selectively detects visible and near‐infrared light with high sensitivity by switching the voltage. Peripheral oxygen saturation (SpO2) measurement is demonstrated using the device attached to a finger under a single light source by ...
Sachi Awakura   +6 more
wiley   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun   +17 more
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

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