Results 261 to 270 of about 663,366 (347)

Diagnostic challenges in biliary cytology of biliary inflammatory pseudotumor of the liver: A case report and a review of the literature. [PDF]

Med Int (Lond)
Higuchi Y, Kato T, Kurihara E, Toyama T, Fusegawa T, Ubukata M, Yoshizawa T, Imaizumi T, Suzuki A, Oshima M, Endo F, Matsumoto S, Hagiwara K, Otake Y, Sugihara S, Tani N, Imai Y.   +16 more
europepmc   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

Advanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin, Mengjie Zhang, Wenying Liu, Wenlong Shen, Debao Li, Hongming Miao, Fang Deng, Gang Zhang, Yi Tian, Yi Zhang, Zhihu Zhao, Bing Ni   +11 more
wiley   +1 more source

pVHL status in clear cell renal cell carcinoma regulates HIF-α and E-cadherin expression levels and their implications for tumor progression. [PDF]

Ups J Med Sci
Sitaram RT, Ljungberg B.
europepmc   +1 more source

CypD Dependent mPTP Opening Is Crucial for Oxidized Mitochondrial DNA Release in Ferroptosis

Advanced Science, EarlyView.
Ferroptosis is driven by mitochondrial permeability transition pore (mPTP) opening, which induces mitochondrial swelling and releases oxidized mitochondrial DNA. The released mtDNA activates cGAS–STING signaling, promotes ferritinophagy, and amplifies ferroptotic cell death. Disruption of mtDNA repair sensitizes tumors to ferroptosis in vivo, revealing
Hong Zhou, Wan Fu, Shizuo Liu, Zili Zhang, Hanyan Luo, Qing Zhong   +5 more
wiley   +1 more source

IGF2BP3-STAT3-METTL3 axis promotes malignant progression in hepatocellular carcinoma (HCC). [PDF]

Hum Genomics
Xu Y, Cao Y, Yang J, Yu X, Yang L, Xie Y, Zhao J, Zhang Y.   +7 more
europepmc   +1 more source

Human Cloning and \u3cem\u3eDonum Vitae\u3c/em\u3e [PDF]

, 1999
Lozano, Alexander J.
core   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

Advanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang, Xu Chen, Haowei Xu, Zhiqi Zeng, Keyu Lu, Yu Mao, Qianru Lv, Hui Shi, Song Liu, Xian Shen, Chunyu Yin, Yang Yang, Yan Guo, Xingyun Wang, Rui Cheng   +14 more
wiley   +1 more source

A novel KRT17-hnRNP K-CXCR3 axis promotes esophageal squamous cell carcinoma metastasis via nuclear-cytoplasmic redistribution. [PDF]

Sci Rep
Yu S, Ye L, Huang J, Xu H, Wu W, Jiang M, Kang M.   +6 more
europepmc   +1 more source

Ethics, Nuclear Terrorism, and Counter-Terrorist Nuclear Reprisals – A Response to John Mark Mattox's 'Nuclear Terrorism: The Other Extreme of Irregular Warfare'

, 2015
Thomas E. Doyle
openalex   +1 more source

An Introduction to the Impact of Information Technology on National Security [PDF]

, 1999
Goss, Porter
core   +1 more source